AASMA-300 XR

# Etofylline 231 mg + Theophylline 69 mg ## Short Description Etofylline 231 mg + Theophylline 69 mg is a **bronchodilator combination** used to help relieve breathing difficulties associated with certain respiratory conditions, including **asthma and chronic obstructive pulmonary disease (COPD)**. Etofylline is a theophylline derivative, while theophylline belongs to the methylxanthine class of bronchodilators. Together, they help relax airway muscles and improve airflow. ## Key Benefits * Helps relax the muscles of the airways * Helps improve airflow through the lungs * May relieve wheezing and chest tightness * Helps reduce breathing difficulty associated with bronchospasm * May support symptom control in asthma and COPD * Provides bronchodilator activity through methylxanthine-related mechanisms ## Uses / Indications Etofylline + Theophylline may be prescribed for: * **Bronchial asthma** * **Chronic obstructive pulmonary disease (COPD)** * Bronchospasm associated with certain respiratory disorders * Wheezing and breathing difficulty caused by reversible airway narrowing It should be used according to a healthcare professional's diagnosis and treatment plan. > **Important:** This medicine is not generally considered a first-choice treatment for sudden, severe asthma attacks. A prescribed rapid-acting rescue inhaler should be used for acute symptoms when appropriate. ## How It Works ### Etofylline Etofylline is a derivative of theophylline that contributes to **bronchodilation**, helping relax airway smooth muscle. ### Theophylline Theophylline is a **methylxanthine bronchodilator**. It helps relax bronchial smooth muscle and can improve airflow. It also has effects on respiratory muscle function and inflammatory pathways. ### Combined Action The combination helps reduce airway narrowing and may make breathing easier by promoting **relaxation of bronchial muscles**. ## Dosage & Administration * Take exactly as prescribed by your doctor * The dose depends on the patient's age, weight, medical condition and formulation * Take the medicine at the same time each day if scheduled regularly * Swallow tablets whole if they are modified-release or extended-release formulations * Do not crush or chew modified-release tablets unless the product instructions specifically allow it * Take with or without food according to the product instructions, but try to take it consistently in relation to meals * Do not take more than the prescribed dose * Do not stop long-term treatment without medical advice * If you miss a dose, take it when remembered unless it is nearly time for the next dose * Do not double the next dose Because **theophylline has a relatively narrow therapeutic range**, some patients may require blood-level monitoring. ## Side Effects Possible side effects include: * Nausea * Vomiting * Stomach discomfort * Headache * Restlessness * Nervousness * Tremor * Difficulty sleeping * Increased heart rate * Palpitations Excessive theophylline levels can cause serious toxicity, including: * Persistent vomiting * Severe tremor * Severe agitation * Irregular heartbeat * Very rapid heartbeat * Low blood pressure * Seizures Seek urgent medical attention if severe symptoms or signs of overdose occur. ## Precautions & Warnings * Use exactly as prescribed because theophylline can have a **narrow therapeutic range** * Tell your doctor if you have heart disease or an abnormal heart rhythm * Tell your doctor if you have a seizure disorder * Inform your doctor if you have liver disease * Inform your doctor if you have kidney problems * Tell your doctor if you have an overactive thyroid * Use caution in older adults * Smoking can affect the metabolism of theophylline and may alter its effectiveness * Changes in smoking habits should be reported to your healthcare professional * Avoid excessive caffeine because caffeine and theophylline can produce additive effects * Tell your doctor if you develop persistent vomiting or fever * Do not use this medicine to manage a sudden severe asthma attack unless specifically instructed * Tell your doctor if you are pregnant, planning pregnancy or breastfeeding ### Important Warning Theophylline toxicity can be serious. Symptoms such as **persistent vomiting, severe palpitations, marked tremor, confusion or seizures** require urgent medical attention. ## Drug Interactions Theophylline can interact with many medicines. Important examples include: * **Ciprofloxacin** — may increase theophylline levels * **Erythromycin** — may increase theophylline levels * **Clarithromycin** — may increase theophylline levels * **Fluvoxamine** — may increase theophylline levels * **Cimetidine** — may increase theophylline levels * Certain anticonvulsants, such as **phenytoin and carbamazepine**, may reduce theophylline levels * **Rifampicin** may reduce theophylline levels * Other methylxanthines or caffeine-containing products may increase adverse effects * Beta-agonist bronchodilators may increase cardiovascular side effects * Some medicines affecting liver enzymes can significantly change theophylline concentrations Always tell your doctor or pharmacist about **all prescription medicines, OTC medicines, supplements and herbal products** you use. ## Storage Information * Store according to the manufacturer's instructions * Keep in a cool, dry place * Protect from excessive heat, moisture and direct sunlight * Keep the container tightly closed * Keep out of reach and sight of children * Do not use after the expiry date * Keep the medicine in its original packaging ## Prescription Status Etofylline + Theophylline is generally treated as a **prescription medicine**, although regulations may vary by country and formulation. Because theophylline has a narrow therapeutic range and numerous drug interactions, medical supervision is recommended. ## Genuine Medicine Assurance * Purchase the medicine from a licensed and reputable pharmacy * Check the active ingredients and strengths * Verify the manufacturer's name * Check the batch number and expiry date * Ensure the packaging and seal are intact * Do not purchase medicines from unverified sellers * Do not use medicines with damaged or suspicious packaging * Store the medicine according to the manufacturer's instructions * If you suspect a product is counterfeit, consult a pharmacist or the appropriate medicine regulatory authority ## Frequently Asked Questions ### What is Etofylline 231 mg + Theophylline 69 mg used for? It is a bronchodilator combination used to help manage **breathing difficulties and bronchospasm associated with conditions such as asthma and COPD**. ### Is Etofylline a bronchodilator? Yes. Etofylline is a theophylline derivative that contributes to bronchodilation and helps relax airway muscles. ### What does Theophylline do? Theophylline helps relax bronchial smooth muscle, which can improve airflow and reduce airway obstruction. ### Can Etofylline + Theophylline treat asthma? It may be prescribed as part of asthma management in selected patients. However, treatment should be individualized, and it is not generally the preferred rescue treatment for a sudden severe asthma attack. ### Can this medicine treat COPD? Yes. Etofylline and theophylline may be used in selected patients with COPD to help improve airflow and control respiratory symptoms. ### Does Etofylline + Theophylline provide immediate relief? It is not generally considered a replacement for a rapid-acting rescue inhaler during an acute asthma attack. Follow your asthma or COPD action plan. ### Can I use this medicine during an asthma attack? Do not rely on this medicine for sudden severe breathing difficulty unless specifically instructed by your doctor. Use your prescribed **rescue inhaler** when indicated and seek emergency medical care if symptoms are severe. ### Does Theophylline have side effects? Yes. Common effects include nausea, headache, restlessness, tremor, difficulty sleeping and palpitations. ### Why does Theophylline require careful dosing? Theophylline has a **narrow therapeutic range**, meaning the difference between an effective dose and a toxic dose can be relatively small. ### Can Theophylline cause a fast heartbeat? Yes. Increased heart rate and palpitations can occur, particularly when blood levels become excessive. ### Can Theophylline cause nausea? Yes. Nausea, vomiting and stomach discomfort are relatively common adverse effects. ### Can I drink coffee while taking Theophylline? Caffeine can have additive effects with theophylline and may increase nervousness, tremor, insomnia or palpitations. Limiting excessive caffeine is generally advisable. ### Can I drink alcohol while taking this medicine? Discuss alcohol consumption with your healthcare professional. Alcohol and individual patient factors can affect theophylline handling and adverse effects. ### Does smoking affect Theophylline? Yes. Smoking can increase the metabolism of theophylline and lower its blood concentration. **Stopping or substantially reducing smoking can increase theophylline levels**, so inform your doctor about changes in smoking habits. ### Can antibiotics interact with Theophylline? Yes. Some antibiotics, particularly **ciprofloxacin and macrolide antibiotics such as erythromycin and clarithromycin**, can increase theophylline levels. ### Can I take other medicines with Theophylline? Some medicines are compatible, while others can significantly alter theophylline levels. Always provide your doctor or pharmacist with a complete list of your medicines. ### Does Theophylline require a blood test? Some patients require **theophylline blood-level monitoring**, particularly when high doses are used, symptoms of toxicity occur, interacting medicines are started or stopped, or the patient's clinical condition changes. ### What are the symptoms of Theophylline overdose? Symptoms can include persistent vomiting, severe nausea, tremor, agitation, rapid or irregular heartbeat and seizures. A suspected overdose requires urgent medical attention. ### What happens if I miss a dose? Take the missed dose when remembered unless it is nearly time for your next scheduled dose. Do not double the dose. ### Can children take Etofylline + Theophylline? Children may receive theophylline-based medicines in selected circumstances, but dosing requires careful calculation and medical supervision. ### Can elderly patients take Theophylline? Older adults may be more sensitive to the effects of theophylline and may require careful dosing and monitoring. ### Can this medicine be taken during pregnancy? Tell your doctor if you are pregnant or planning pregnancy. The decision to use the medicine should be based on an individual assessment of benefits and risks. ### Can this medicine be taken while breastfeeding? Consult your healthcare professional before use while breastfeeding because theophylline can pass into breast milk. ### Is Etofylline + Theophylline an antibiotic? No. It is a **bronchodilator**, not an antibiotic. ### Is Etofylline + Theophylline a steroid? No. It is not a corticosteroid. It belongs to the methylxanthine-related bronchodilator group. ### Can this medicine cure asthma? No. Asthma is a chronic condition requiring an individualized treatment plan. This medicine may help control airway narrowing in selected patients but does not cure asthma. ### How should Etofylline + Theophylline be stored? Store it according to the manufacturer's instructions, away from excessive heat and moisture, and keep it out of reach of children. ## Medical Disclaimer This information is provided for general educational and SEO purposes only and is not a substitute for professional medical advice, diagnosis or treatment. **Etofylline + Theophylline should be used only according to a qualified healthcare professional's instructions.** Theophylline has a narrow therapeutic range and numerous potential drug interactions. Seek urgent medical attention for suspected overdose, persistent vomiting, severe palpitations, abnormal heartbeat, confusion or seizures. This medicine should not be relied upon as the sole treatment for a sudden, severe asthma attack. Always verify the exact formulation, strength, dosing instructions and local prescribing requirements on the product label.