AMACE 100

# Aceclofenac 100 mg ## Short Description **Aceclofenac 100 mg** is a **non-steroidal anti-inflammatory drug (NSAID)** used to relieve **pain, swelling, and inflammation** associated with conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It works by reducing the production of substances called prostaglandins that contribute to pain and inflammation. Aceclofenac is generally intended for use at the **lowest effective dose for the shortest appropriate duration**. --- ## Key Benefits * Helps relieve **mild to moderate pain** * Reduces **inflammation and swelling** * Helps improve movement in painful joints * May reduce **joint stiffness** * Commonly used for inflammatory musculoskeletal conditions * Can provide symptomatic relief in conditions such as arthritis --- ## Uses / Indications Aceclofenac 100 mg may be prescribed for the symptomatic treatment of: * **Osteoarthritis** * **Rheumatoid arthritis** * **Ankylosing spondylitis** * Joint and musculoskeletal pain associated with inflammation * Other painful inflammatory conditions when specifically recommended by a healthcare professional Aceclofenac helps control symptoms but **does not cure the underlying arthritis or degenerative joint disease**. --- ## How It Works Aceclofenac is an NSAID that reduces the production of **prostaglandins**, chemical substances involved in pain, inflammation, and fever. By reducing prostaglandin production, aceclofenac helps: * Decrease pain * Reduce inflammation * Reduce swelling * Improve mobility and joint comfort --- ## Dosage & Administration > **Important:** The dosage should be individualized by a healthcare professional, particularly in older adults and people with kidney, liver, cardiovascular, or gastrointestinal problems. ### General Adult Administration The commonly recommended adult dose is: **Aceclofenac 100 mg twice daily**, usually taken approximately 12 hours apart. * Take the tablet exactly as prescribed. * Swallow it whole with sufficient water. * Taking it **with or after food** may help reduce stomach irritation. * Do not exceed the prescribed dose. * Use the lowest effective dose for the shortest duration necessary. ### Missed Dose If you miss a dose, take it when you remember unless it is nearly time for your next dose. **Do not take two doses together** to compensate for a missed dose. ### Important Aceclofenac should not routinely be combined with another NSAID, such as ibuprofen, naproxen, or diclofenac, unless specifically instructed by a healthcare professional. --- ## Side Effects ### Common Side Effects Possible side effects include: * Indigestion * Stomach pain or discomfort * Nausea * Diarrhea * Dizziness * Headache * Heartburn * Gas or bloating ### Serious Side Effects Stop taking the medicine and seek medical attention if you develop: * Severe stomach pain * **Black or bloody stools** * Vomiting blood or material resembling coffee grounds * Severe allergic reaction * Difficulty breathing or swelling of the face, lips, or throat * Severe skin rash, blistering, or peeling * Yellowing of the skin or eyes * Significant reduction in urine output * Chest pain or sudden weakness NSAIDs can cause serious **gastrointestinal bleeding, kidney problems, cardiovascular events, and allergic reactions**, particularly in susceptible individuals or with prolonged/high-dose use. --- ## Precautions & Warnings Before taking Aceclofenac 100 mg, inform your healthcare professional if you have: * A history of **stomach ulcers or gastrointestinal bleeding** * Asthma or previous reactions to aspirin/NSAIDs * Kidney disease * Liver disease * Heart disease * High blood pressure * A history of stroke or heart attack * Blood-clotting disorders * Fluid retention or swelling * Inflammatory bowel disease ### Gastrointestinal Warning Aceclofenac can increase the risk of **stomach ulcers and gastrointestinal bleeding**. The risk may be higher in older adults and people taking corticosteroids, anticoagulants, antiplatelet medicines, or certain antidepressants. ### Cardiovascular Warning NSAIDs may increase the risk of **heart attack or stroke**, particularly with higher doses and longer treatment durations. People with cardiovascular disease or cardiovascular risk factors should discuss the risks with their doctor before using aceclofenac. ### Kidney Warning NSAIDs can reduce kidney function, particularly in people who are dehydrated or have existing kidney disease or heart failure. ### Pregnancy Aceclofenac should generally be **avoided during pregnancy unless specifically prescribed by a healthcare professional**. NSAIDs should not be used during the later stages of pregnancy because they may cause serious complications for the fetus and mother. If you are pregnant, planning pregnancy, or breastfeeding, consult your healthcare professional before using aceclofenac. --- ## Drug Interactions Tell your doctor or pharmacist about all medicines you take. Important potential interactions include: * **Other NSAIDs** such as ibuprofen, naproxen, diclofenac, or aspirin — increased risk of gastrointestinal and other adverse effects. * **Anticoagulants** such as warfarin — increased risk of bleeding. * **Antiplatelet medicines** such as clopidogrel — increased bleeding risk. * **Corticosteroids** such as prednisolone — increased risk of gastrointestinal ulcers and bleeding. * **SSRIs/SNRIs** — may increase gastrointestinal bleeding risk. * **ACE inhibitors and ARBs** — may reduce blood-pressure control and increase kidney-related risks. * **Diuretics** — may reduce their effectiveness and increase the risk of kidney problems. * **Lithium** — NSAIDs may increase lithium concentrations. * **Methotrexate** — may increase methotrexate-related toxicity. * **Cyclosporine or tacrolimus** — may increase the risk of kidney toxicity. * **Digoxin** — NSAIDs may affect digoxin levels in some circumstances. This is not a complete list. Always inform your healthcare professional about prescription medicines, OTC medicines, vitamins, and herbal supplements you use. --- ## Storage Information * Store at **room temperature** according to the product label. * Keep away from excessive heat, moisture, and direct sunlight. * Keep the tablets in their original packaging. * Keep the container tightly closed. * Keep out of reach and sight of children. * Do not use after the expiry date. * Dispose of unused or expired medicines appropriately according to local recommendations. --- ## Prescription Status **Aceclofenac 100 mg is generally a prescription medicine**, although regulations may vary between countries. Because NSAIDs can cause gastrointestinal, kidney, cardiovascular, and allergic complications, aceclofenac should be used according to the advice of a qualified healthcare professional. --- ## Genuine Medicine Assurance When purchasing Aceclofenac 100 mg: * Purchase from a **licensed and reputable pharmacy** or authorized medicine supplier. * Check that the packaging is intact and properly sealed. * Verify the **medicine name, strength, batch number, manufacturing details, and expiry date**. * Ensure the tablets and packaging match the prescribed medicine. * Do not use tablets from damaged, opened, or suspicious packaging. * Avoid purchasing medicines from unauthorized sources. * If you suspect a medicine may be counterfeit, consult a pharmacist or contact the manufacturer using the information printed on the original packaging. --- # FAQ – Aceclofenac 100 mg ### 1. What is Aceclofenac 100 mg used for? Aceclofenac 100 mg is an NSAID used to relieve **pain and inflammation**, particularly in conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. ### 2. Is Aceclofenac a painkiller? Yes. Aceclofenac is an **NSAID painkiller** that also has anti-inflammatory effects. It helps reduce pain, swelling, and inflammation. ### 3. Is Aceclofenac an anti-inflammatory medicine? Yes. Aceclofenac reduces the production of prostaglandins, which are involved in inflammation and pain. ### 4. Can Aceclofenac 100 mg be used for back pain? It may be prescribed for certain types of **acute or inflammatory back and musculoskeletal pain**. Persistent, severe, or unexplained back pain should be medically evaluated. ### 5. Can Aceclofenac 100 mg be used for arthritis? Yes. It is commonly prescribed for symptomatic relief of **osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis**. ### 6. Should Aceclofenac 100 mg be taken after food? Aceclofenac is commonly taken **with or after food** to help reduce stomach irritation. Follow the instructions provided with your specific prescription. ### 7. Can I take Ibuprofen with Aceclofenac? Generally, **do not combine aceclofenac with ibuprofen or another NSAID** unless your healthcare professional specifically tells you to do so. Combining NSAIDs can increase the risk of stomach bleeding, kidney problems, and other adverse effects. ### 8. Can I take Aceclofenac with Paracetamol? Paracetamol and aceclofenac work differently and may sometimes be prescribed together. However, the combination should be used according to professional advice, particularly if you have liver, kidney, stomach, or cardiovascular problems. ### 9. Does Aceclofenac cause stomach problems? Yes. Aceclofenac may cause **indigestion, stomach pain, nausea, heartburn, ulcers, or gastrointestinal bleeding**. Taking it with food may reduce stomach discomfort but does not eliminate the risk of serious gastrointestinal complications. ### 10. Can Aceclofenac cause kidney problems? Yes. NSAIDs can affect kidney function, particularly in people with kidney disease, dehydration, heart failure, or those taking certain medicines such as diuretics or ACE inhibitors. ### 11. Can Aceclofenac increase blood pressure? It can cause **fluid retention or reduced effectiveness of some blood-pressure medicines**, potentially increasing blood pressure in some people. ### 12. Can I take Aceclofenac if I have a stomach ulcer? Aceclofenac may increase the risk of ulcers and gastrointestinal bleeding. If you have a current or previous stomach ulcer or gastrointestinal bleeding, consult your doctor before taking it. ### 13. Can Aceclofenac be taken during pregnancy? Aceclofenac should generally be avoided during pregnancy unless specifically recommended by a healthcare professional. NSAIDs are particularly concerning during later pregnancy. ### 14. Can I drink alcohol while taking Aceclofenac? It is advisable to **limit or avoid alcohol**, particularly with regular or high-dose NSAID treatment. Alcohol can increase gastrointestinal irritation and may increase the risk of gastrointestinal bleeding. ### 15. How long can I take Aceclofenac 100 mg? Use it for the **shortest duration necessary at the lowest effective dose**. Long-term treatment should be monitored by a healthcare professional because the risks of gastrointestinal, cardiovascular, kidney, and other adverse effects can increase with prolonged use. ### 16. What happens if I take too much Aceclofenac? An overdose may cause nausea, vomiting, stomach pain, dizziness, gastrointestinal bleeding, kidney problems, or other serious effects. Seek **urgent medical advice** if you have taken more than prescribed. ### 17. Does Aceclofenac make you sleepy? Dizziness or drowsiness can occur in some people. If you experience these effects, avoid driving or operating machinery until you know how the medicine affects you. ### 18. What should I do if I miss an Aceclofenac dose? Take the missed dose when you remember unless it is nearly time for your next dose. **Do not take a double dose** to make up for the missed dose. --- ## Medical Disclaimer This information is provided for **educational and informational purposes only** and is not a substitute for professional medical advice, diagnosis, or treatment. Aceclofenac 100 mg should be used according to the prescription and instructions provided by a qualified healthcare professional. NSAIDs can cause potentially serious **gastrointestinal bleeding, kidney problems, cardiovascular complications, and allergic reactions**. Use the lowest effective dose for the shortest appropriate duration. Do not combine aceclofenac with other NSAIDs unless specifically advised by your healthcare professional. Seek urgent medical attention for chest pain, difficulty breathing, severe allergic reactions, vomiting blood, black stools, or other serious symptoms.