APREZO 30MG
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Description
APREZO 30MG TAB 10
Details
Composition
APREMILAST 30
# Apremilast 30 mg
## Short Description
**Apremilast 30 mg** is a **prescription oral immunomodulatory medicine** used for the treatment of **psoriasis, psoriatic arthritis, and certain inflammatory skin conditions**. It belongs to a class of medicines called **phosphodiesterase-4 (PDE4) inhibitors**.
Apremilast works by regulating inflammatory pathways in the immune system, helping reduce inflammation, skin lesions, joint symptoms, and disease-related discomfort.
> **Important:** Apremilast should be used only under the supervision of a healthcare professional. Regular monitoring may be required, especially for weight changes, mood changes, and treatment response.
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# Key Benefits Section
- Helps reduce symptoms of plaque psoriasis.
- Helps manage psoriatic arthritis symptoms.
- Reduces inflammation caused by overactive immune responses.
- Helps improve skin redness, scaling, and irritation.
- Supports reduction of joint pain and stiffness associated with psoriatic arthritis.
- Convenient oral treatment option.
- Does not require routine blood monitoring like some traditional immunosuppressive medicines.
- Helps improve quality of life in chronic inflammatory conditions.
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# Uses / Indications
Apremilast 30 mg may be used for:
## Plaque Psoriasis
Used for adults with:
- Moderate to severe plaque psoriasis.
- Red, thick, scaly skin patches.
- Chronic inflammatory skin symptoms.
## Psoriatic Arthritis
Used to help manage:
- Joint pain.
- Joint stiffness.
- Swelling.
- Reduced mobility associated with psoriatic arthritis.
## Oral Ulcers Associated with Behçet’s Disease
In some regions, Apremilast may also be approved for:
- Recurrent oral ulcers associated with Behçet’s disease.
> **Note:** Use depends on individual diagnosis and local regulatory approval.
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# How It Works
Apremilast belongs to the **PDE4 inhibitor** class.
It works by:
- Blocking the enzyme **phosphodiesterase-4 (PDE4)**.
- Increasing levels of cyclic AMP (cAMP) inside immune cells.
- Regulating the production of inflammatory chemicals.
- Reducing excessive immune system activity.
- Lowering inflammation responsible for psoriasis and psoriatic arthritis symptoms.
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# Dosage & Administration
Always take **Apremilast 30 mg** exactly as prescribed by your healthcare provider.
## General Guidelines
- Taken orally with water.
- Usually taken twice daily after an initial dose adjustment period.
- Can be taken with or without food.
- Swallow tablets whole.
## Dose Adjustment
- A lower dose may be required in patients with severe kidney impairment.
- Dose changes should only be made by a healthcare professional.
## Important Advice
- Take regularly for the best results.
- Do not stop treatment without consulting your doctor.
- Improvement may take several weeks.
## Missed Dose
- Take the missed dose when remembered.
- If it is close to the next dose, skip it.
- Do not take two doses together.
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# Side Effects
Like all medicines, Apremilast 30 mg may cause side effects.
## Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Headache
- Upper respiratory tract infection
- Stomach discomfort
- Decreased appetite
## Other Possible Side Effects
- Weight loss
- Fatigue
- Dizziness
## Serious Side Effects (Seek Medical Attention)
- Severe allergic reactions.
- Significant unexplained weight loss.
- New or worsening depression.
- Suicidal thoughts or unusual mood changes.
- Severe diarrhea or dehydration.
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# Precautions & Warnings
Before taking Apremilast, inform your healthcare provider if you have:
- Kidney problems.
- History of depression or mood disorders.
- Unexplained weight loss.
- Pregnancy or breastfeeding status.
- Allergies to Apremilast or tablet ingredients.
## Important Warnings
- Monitor body weight during treatment.
- Inform your doctor if appetite decreases significantly.
- Report mood changes, depression, or suicidal thoughts immediately.
- Use caution in patients with severe kidney impairment.
- Do not share this medicine with others.
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# Drug Interactions
Apremilast may interact with medicines that affect its breakdown in the body.
## Medicines That May Reduce Apremilast Effectiveness
- Rifampicin
- Carbamazepine
- Phenytoin
- Phenobarbital
These medicines may lower Apremilast levels and reduce its effectiveness.
## Other Medicines
Always inform your healthcare provider about:
- Prescription medicines.
- Over-the-counter medicines.
- Vitamins.
- Herbal supplements.
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# Storage Information
- Store below **30°C** or according to manufacturer instructions.
- Keep in a cool, dry place.
- Protect from moisture and direct sunlight.
- Keep tablets in the original packaging.
- Keep out of reach of children.
- Do not use after the expiry date.
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# Prescription Status
**Prescription Only Medicine (Rx)**
Apremilast 30 mg should only be used under the supervision of a qualified healthcare professional experienced in treating inflammatory conditions.
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# Genuine Medicine Assurance
We provide **100% genuine, quality-assured medicines** sourced from authorized pharmaceutical manufacturers and licensed distributors. Every product is stored and handled according to recommended pharmaceutical standards to help maintain its quality, safety, and effectiveness.
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# Frequently Asked Questions (FAQ)
## 1. What is Apremilast 30 mg used for?
Apremilast 30 mg is used for plaque psoriasis, psoriatic arthritis, and certain inflammatory conditions.
## 2. Is Apremilast an immunosuppressant?
Apremilast regulates immune activity but works differently from traditional strong immunosuppressants.
## 3. How does Apremilast work?
It blocks PDE4 enzymes and reduces the production of inflammatory substances in the body.
## 4. How long does Apremilast take to work?
Improvement may begin within a few weeks, but maximum benefits may take longer.
## 5. Can Apremilast cure psoriasis?
No. It helps control symptoms and reduce inflammation but does not permanently cure psoriasis.
## 6. Does Apremilast cause weight loss?
Weight loss may occur in some patients. Regular weight monitoring is recommended.
## 7. Can Apremilast be taken with food?
Yes. It can generally be taken with or without food.
## 8. Can Apremilast be used during pregnancy?
Consult your healthcare provider before using Apremilast during pregnancy or breastfeeding.
## 9. Does Apremilast require blood tests?
Routine blood monitoring is generally not required, but your doctor may recommend monitoring based on your condition.
## 10. Can Apremilast cause diarrhea?
Yes. Diarrhea is one of the most common side effects, especially during the initial treatment period.
## 11. Can Apremilast be stopped suddenly?
Do not stop without medical advice. Your symptoms may return or worsen.
## 12. Is Apremilast a steroid?
No. Apremilast is not a steroid. It is a PDE4 inhibitor.
## 13. Can Apremilast help joint pain?
Yes. It may reduce joint pain, stiffness, and inflammation in psoriatic arthritis.
## 14. When should I contact a doctor?
Contact your healthcare provider for severe diarrhea, significant weight loss, allergic reactions, depression, or unusual mood changes.
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# Medical Disclaimer
The information provided on this page is intended for **educational and informational purposes only** and should not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. **Apremilast 30 mg** should be used only under medical supervision, with appropriate monitoring for side effects and treatment response.
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