ASOMEX-AT

# Atenolol 50 mg + S-Amlodipine 2.5 mg ## SHORT DESCRIPTION Atenolol 50 mg + S-Amlodipine 2.5 mg is a combination medicine used to manage **high blood pressure (hypertension)** and, in appropriate patients, certain heart-related conditions such as angina. Atenolol is a beta-blocker, while S-Amlodipine is the active S-enantiomer of amlodipine and belongs to the calcium channel blocker group. Together, they help reduce blood pressure and decrease the workload on the heart. ## KEY BENEFITS * Helps lower and control high blood pressure * Reduces the workload and oxygen demand of the heart * May help prevent symptoms of stable angina in appropriate patients * Helps slow an excessively fast heart rate * Provides complementary blood pressure-lowering effects * May help reduce the risk of complications associated with uncontrolled hypertension ## USES / INDICATIONS Atenolol 50 mg + S-Amlodipine 2.5 mg may be prescribed for: * Hypertension * Stable angina pectoris * High blood pressure requiring combination therapy * Certain patients with increased heart rate or cardiovascular workload, when clinically appropriate Treatment should be combined with appropriate lifestyle measures such as a balanced diet, regular physical activity, and reduced sodium intake when recommended. ## HOW IT WORKS **Atenolol:** Atenolol is a selective beta-1 adrenergic receptor blocker. It slows the heart rate and reduces the force with which the heart contracts. This lowers cardiac workload and blood pressure and reduces the heart's oxygen requirement. **S-Amlodipine:** S-Amlodipine blocks L-type calcium channels in vascular smooth muscle. It relaxes and widens blood vessels, reducing peripheral vascular resistance and helping lower blood pressure. Together, the two medicines lower blood pressure through complementary mechanisms. ## DOSAGE & ADMINISTRATION * Take Atenolol 50 mg + S-Amlodipine 2.5 mg exactly as prescribed by your doctor. * It is generally taken **once daily**, preferably at the same time each day. * The medicine may generally be taken with or without food. * Swallow the tablet with water; do not crush or chew it unless specifically instructed. * Do not stop atenolol suddenly, particularly if you have heart disease, as abrupt withdrawal may worsen certain heart conditions. * Your doctor may monitor blood pressure and heart rate regularly. * Dose adjustments may be required depending on your response, age, kidney function, and other medical conditions. ## SIDE EFFECTS Possible side effects may include: * Dizziness * Tiredness or weakness * Headache * Slow heartbeat * Low blood pressure * Cold hands and feet * Ankle or leg swelling * Flushing * Nausea * Sleep disturbances Seek medical attention for severe breathing difficulty, fainting, very slow heartbeat, severe chest pain, or significant swelling. ## PRECAUTIONS & WARNINGS * Inform your doctor if you have asthma, chronic obstructive pulmonary disease, diabetes, heart failure, or circulation problems. * Tell your doctor if you have a slow heart rate, low blood pressure, or certain heart conduction disorders. * Atenolol may mask some warning signs of low blood sugar, particularly a rapid heartbeat, in people with diabetes. * Patients with kidney impairment may require dose adjustment because atenolol is primarily eliminated through the kidneys. * S-Amlodipine may cause ankle or leg swelling. * Rise slowly from sitting or lying down if you experience dizziness. * Do not stop atenolol abruptly without medical supervision. * Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. * Tell your healthcare professional before surgery or if you are receiving anaesthesia. ## DRUG INTERACTIONS This combination may interact with: * Other medicines that lower blood pressure * Other beta-blockers * Verapamil or diltiazem * Digoxin * Certain antiarrhythmic medicines * Insulin and other medicines used to treat diabetes * Some medicines that affect heart rate or blood pressure * Certain medicines that affect liver enzyme activity Combining atenolol with other medicines that slow the heart rate may increase the risk of excessive bradycardia or heart conduction problems. Always inform your doctor or pharmacist about all prescription medicines, over-the-counter medicines, vitamins, and supplements you take. ## STORAGE INFORMATION * Store at room temperature according to the manufacturer's instructions. * Keep away from excessive heat, moisture, and direct sunlight. * Keep the medicine in its original packaging. * Keep out of reach and sight of children. * Do not use after the expiry date printed on the package. * Keep the packaging tightly closed when not in use. ## PRESCRIPTION STATUS Atenolol 50 mg + S-Amlodipine 2.5 mg is generally a **prescription medicine**. It should be used under the supervision of a qualified healthcare professional because blood pressure and heart rate may require monitoring. ## GENUINE MEDICINE ASSURANCE For genuine medicine assurance: * Purchase the medicine from a licensed and reputable pharmacy. * Check the product name, strength, batch number, manufacturer details, and expiry date. * Ensure the packaging and seal are intact. * Do not use products with damaged, altered, or suspicious packaging. * Store the medicine according to the manufacturer's instructions. * Consult a pharmacist if you have concerns about product authenticity. ## FAQ ### What is Atenolol 50 mg + S-Amlodipine 2.5 mg used for? It is primarily used to control high blood pressure. It may also be prescribed for stable angina or certain cardiovascular conditions when both medicines are appropriate. ### Is Atenolol a beta-blocker? Yes. Atenolol is a selective beta-1 blocker that reduces heart rate and cardiac workload, helping lower blood pressure and reduce the heart's oxygen demand. ### What is S-Amlodipine? S-Amlodipine is the active S-enantiomer of amlodipine. It is a calcium channel blocker that relaxes blood vessels and helps reduce blood pressure. ### Can Atenolol and S-Amlodipine be taken together? Yes. They can be combined because they lower blood pressure through different mechanisms. The combination should be taken only as prescribed by a healthcare professional. ### Does Atenolol + S-Amlodipine lower heart rate? Atenolol can lower heart rate. S-Amlodipine primarily relaxes blood vessels and generally has much less effect on heart rate. Your doctor may monitor your pulse during treatment. ### When should I take Atenolol + S-Amlodipine? It is generally taken once daily at approximately the same time each day. Follow your doctor's specific instructions. ### Can I take Atenolol + S-Amlodipine with food? Yes. This combination can generally be taken with or without food. Taking it consistently at the same time each day is recommended. ### Can this medicine cause dizziness? Yes. Dizziness may occur, particularly when blood pressure becomes lower than usual or when treatment is first started. Rise slowly from sitting or lying positions. ### Can Atenolol cause a slow heartbeat? Yes. Atenolol reduces heart rate as part of its therapeutic action. If you experience an unusually slow heartbeat, fainting, severe dizziness, or weakness, contact your healthcare professional. ### Can Atenolol be stopped suddenly? No. Atenolol should generally not be stopped suddenly, particularly in people with coronary artery disease, because abrupt discontinuation can worsen angina or other heart problems. Your doctor can advise on gradual dose reduction when appropriate. ### Can this medicine cause ankle swelling? Yes. S-Amlodipine can cause swelling of the ankles or feet. Inform your doctor if swelling is persistent, severe, or accompanied by breathing difficulty. ### Can people with diabetes take Atenolol + S-Amlodipine? People with diabetes may be able to use this combination, but atenolol can mask some symptoms of low blood sugar, especially a rapid heartbeat. Blood glucose should be monitored as advised by your healthcare professional. ### Can I take this medicine during pregnancy? Tell your doctor if you are pregnant or planning pregnancy. Your healthcare professional will determine whether this combination is appropriate and may recommend an alternative depending on your circumstances. ### What should I do if I miss a dose? Take the missed dose when you remember unless it is nearly time for your next dose. Do not take two doses together to make up for a missed dose. ### Does Atenolol + S-Amlodipine cure high blood pressure? It helps control high blood pressure but does not permanently cure hypertension. Long-term treatment, together with healthy lifestyle measures, may be necessary to maintain blood pressure control. ## MEDICAL DISCLAIMER This information is provided for educational and informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Atenolol 50 mg + S-Amlodipine 2.5 mg should be used only as directed by a qualified healthcare professional. The appropriate dose may vary according to blood pressure, heart rate, kidney function, age, medical conditions, and other medicines being used. Do not start, stop, or change the dose without medical advice. Always read the product label and consult your doctor or pharmacist for personalized guidance.