BIGOMET-SR 1000MG

# Metformin SR 1 g (1000 mg) ## Short Description **Metformin SR 1 g (1000 mg)** is a **prescription extended-release (sustained-release) oral antidiabetic medicine** used primarily for the management of **Type 2 Diabetes Mellitus**. It belongs to the **biguanide** class of medicines and helps lower blood sugar by reducing glucose production in the liver, improving the body's response to insulin, and decreasing glucose absorption from the intestines. The **SR (Sustained-Release)** formulation provides gradual release of the medicine, helping maintain blood glucose control while reducing gastrointestinal side effects in some patients. > **Important:** Metformin SR is intended for the treatment of **Type 2 Diabetes** and is **not recommended for the treatment of Type 1 Diabetes or diabetic ketoacidosis.** --- # Key Benefits Section - Helps lower blood glucose levels in adults with Type 2 Diabetes. - Improves the body's sensitivity to insulin. - Reduces glucose production by the liver. - Supports long-term blood sugar control. - Lower risk of causing hypoglycemia when used alone. - Extended-release formulation may improve gastrointestinal tolerability. - May support modest weight neutrality or weight reduction in some patients. - Helps reduce the risk of diabetes-related complications when combined with a healthy lifestyle. --- # Uses / Indications Metformin SR 1 g is indicated for: ### Type 2 Diabetes Mellitus - Blood glucose control in adults with Type 2 Diabetes - Initial or add-on therapy when diet and exercise alone are insufficient ### Combination Therapy - May be used with: - Other oral antidiabetic medicines - GLP-1 receptor agonists - SGLT2 inhibitors - DPP-4 inhibitors - Insulin, when prescribed ### Other Uses - May be prescribed for certain other conditions, such as **polycystic ovary syndrome (PCOS)** or **prediabetes**, based on a healthcare provider's assessment. > **Note:** The use of Metformin for PCOS or prediabetes depends on individual clinical circumstances and local treatment guidelines. --- # How It Works Metformin belongs to the **biguanide** class of medicines. It helps control blood sugar through several mechanisms: - Reduces glucose production by the liver (decreases hepatic gluconeogenesis). - Improves insulin sensitivity in muscle and fat tissues. - Enhances glucose uptake by body cells. - Decreases glucose absorption from the intestine. - Does **not** stimulate excessive insulin release, making hypoglycemia less likely when used alone. The sustained-release formulation gradually releases the medicine over time, helping maintain more consistent blood levels. --- # Dosage & Administration Always take **Metformin SR 1 g** exactly as prescribed by your healthcare provider. ### General Guidelines - Take **with or immediately after food**, preferably with the evening meal if prescribed once daily. - Swallow the tablet whole with water. - **Do not crush, chew, or split** the sustained-release tablet unless advised by your healthcare provider. - Take the medicine at the same time each day. - Continue following your recommended diet and exercise plan. ### Missed Dose - Take the missed dose as soon as you remember. - If it is almost time for the next scheduled dose, skip the missed dose. - Do not take two doses together. ### Important Advice - Regular monitoring of blood glucose and HbA1c is important. - Kidney function should be assessed before starting treatment and monitored periodically thereafter. - Your healthcare provider may gradually increase the dose to improve tolerability. --- # Side Effects Like all medicines, Metformin SR may cause side effects, although not everyone experiences them. ## Common Side Effects - Nausea - Diarrhea - Stomach discomfort - Bloating - Loss of appetite - Metallic taste in the mouth - Mild abdominal pain These side effects often improve after continued use or dose adjustment. ## Less Common Side Effects - Vitamin B12 deficiency with long-term use - Weakness - Weight loss - Skin rash ## Serious Side Effects (Seek Immediate Medical Attention) - **Lactic acidosis** (rare but potentially life-threatening), with symptoms such as: - Severe weakness - Difficulty breathing - Persistent vomiting - Severe abdominal pain - Muscle pain - Unusual drowsiness - Severe allergic reactions - Significant reduction in kidney function --- # Precautions & Warnings Before taking Metformin SR, inform your healthcare provider if you: - Have kidney disease. - Have liver disease. - Have heart failure. - Consume excessive alcohol. - Have dehydration. - Have severe infection. - Are scheduled for surgery. - Are undergoing imaging tests requiring iodinated contrast dye. - Are pregnant or breastfeeding. ### Important Warnings - Kidney function should be evaluated before starting treatment and monitored regularly. - Avoid excessive alcohol intake, as it increases the risk of lactic acidosis. - Temporary discontinuation may be required before certain imaging procedures involving iodinated contrast media and before major surgery, as advised by your healthcare provider. - Long-term use may reduce Vitamin B12 levels; periodic monitoring may be recommended. - Continue healthy eating, regular exercise, and weight management as part of your diabetes care plan. --- # Drug Interactions Metformin SR may interact with: ### Diabetes Medicines - Insulin - Sulfonylureas (e.g., glimepiride, gliclazide) - Other oral antidiabetic medicines ### Other Medicines - Iodinated contrast agents - Corticosteroids - Diuretics - ACE inhibitors - Beta-blockers - Cimetidine - Certain medicines affecting kidney function - Alcohol Always inform your healthcare provider about all prescription medicines, over-the-counter products, vitamins, and herbal supplements you are taking. --- # Storage Information - Store below **30°C** in a cool, dry place. - Protect from moisture and direct sunlight. - Keep the tablets in the original packaging. - Keep out of reach of children. - Do not use after the expiry date. --- # Prescription Status **Prescription Only Medicine (Rx)** Metformin SR 1 g should only be used under the supervision of a qualified healthcare professional. --- # Genuine Medicine Assurance We provide **100% genuine, quality-assured medicines** sourced from authorized pharmaceutical manufacturers and licensed distributors. Every product is stored and handled according to recommended pharmaceutical standards to help maintain its quality, safety, and effectiveness. --- # Frequently Asked Questions (FAQ) ## 1. What is Metformin SR 1 g used for? Metformin SR 1 g is primarily used to improve blood sugar control in adults with **Type 2 Diabetes Mellitus** alongside diet and exercise. ## 2. What does "SR" mean? **SR** stands for **Sustained Release**, meaning the medicine is released gradually over time to provide longer-lasting blood glucose control and may reduce stomach-related side effects in some patients. ## 3. How does Metformin lower blood sugar? It decreases glucose production by the liver, improves insulin sensitivity, increases glucose uptake by tissues, and reduces intestinal glucose absorption. ## 4. Can Metformin cause low blood sugar? When taken alone, Metformin rarely causes hypoglycemia. However, the risk increases when it is combined with insulin or certain other diabetes medicines. ## 5. Should I take Metformin with food? Yes. Taking Metformin SR with food helps reduce stomach upset and improves tolerability. ## 6. Can Metformin help with weight loss? Metformin is generally considered weight-neutral and may contribute to modest weight loss in some people, particularly when combined with healthy lifestyle changes. ## 7. Can I drink alcohol while taking Metformin? Avoid excessive alcohol consumption, as it may increase the risk of **lactic acidosis**, a rare but serious side effect. ## 8. Can Metformin cause Vitamin B12 deficiency? Yes. Long-term use may reduce Vitamin B12 absorption. Your healthcare provider may recommend periodic monitoring, especially if you develop anemia or nerve-related symptoms. ## 9. Is Metformin safe during pregnancy? The decision to use Metformin during pregnancy depends on your medical condition. Consult your healthcare provider for individualized advice. ## 10. Can Metformin be used for Type 1 Diabetes? No. Metformin is **not a substitute for insulin** in people with Type 1 Diabetes. ## 11. What should I do if I miss a dose? Take the missed dose when remembered unless it is almost time for your next dose. Do not take two doses together. ## 12. Why shouldn't I crush the SR tablet? Crushing or chewing a sustained-release tablet can release the medicine too quickly, reducing its intended extended-release effect and increasing the risk of side effects. ## 13. How should I store Metformin SR tablets? Store below 30°C in a cool, dry place, protected from moisture and sunlight, and keep out of reach of children. ## 14. When should I seek immediate medical attention? Seek emergency medical care if you develop symptoms of **lactic acidosis**, severe allergic reactions, persistent vomiting, difficulty breathing, severe weakness, or signs of worsening kidney problems. --- # Medical Disclaimer The information provided on this page is intended for **educational and informational purposes only** and should not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. **Metformin SR 1 g (1000 mg)** should only be used as prescribed by a licensed healthcare professional. Seek immediate medical attention if you experience symptoms of lactic acidosis, severe allergic reactions, or other serious adverse effects. ```