CANDITRAL SB 130

# Itraconazole 130 mg ## Short Description **Itraconazole 130 mg** is a **prescription triazole antifungal medicine** used to treat a wide range of **fungal infections** affecting the skin, nails, mouth, lungs, and other parts of the body caused by susceptible fungi. It works by inhibiting fungal cell membrane formation, preventing fungal growth and eliminating the infection. Itraconazole 130 mg is commonly prescribed for **dermatophyte infections, candidiasis, pityriasis versicolor, and onychomycosis (fungal nail infections)**, as well as certain systemic fungal infections when appropriate. > **Note:** The **130 mg strength** is available in some formulations designed to improve absorption. Always use the specific product exactly as prescribed by your healthcare provider, as different itraconazole formulations are **not interchangeable**. --- # Key Benefits - Effectively treats a broad range of fungal infections. - Eliminates susceptible dermatophytes, yeasts, and certain molds. - Helps relieve itching, redness, scaling, and discomfort caused by fungal infections. - Effective for skin, nail, and mucosal fungal infections. - May also be used for selected systemic fungal infections under specialist supervision. - Helps prevent recurrence when the full treatment course is completed. - Available in enhanced-absorption formulations for improved drug exposure. - Well-established antifungal therapy with proven clinical efficacy. --- # Uses / Indications Itraconazole 130 mg is indicated for the treatment of susceptible fungal infections, including: - Ringworm (Tinea corporis) - Athlete's foot (Tinea pedis) - Jock itch (Tinea cruris) - Fungal nail infections (Onychomycosis) - Pityriasis (Tinea) versicolor - Oral candidiasis (in selected cases) - Vulvovaginal candidiasis (when appropriate) - Certain deep or systemic fungal infections, such as: - Aspergillosis (selected patients) - Histoplasmosis - Blastomycosis - Sporotrichosis - Other susceptible fungal infections as determined by a healthcare provider. > **Important:** Itraconazole is **not effective against viral or bacterial infections**. --- # How It Works Itraconazole belongs to the **triazole antifungal** class. It works by: - Inhibiting the fungal enzyme **14-alpha-demethylase (CYP51)**. - Blocking the production of **ergosterol**, an essential component of the fungal cell membrane. - Disrupting the integrity and function of the fungal cell membrane. - Preventing fungal growth and reproduction, ultimately leading to the elimination of susceptible fungi. This targeted action helps resolve fungal infections while limiting damage to human cells. --- # Dosage & Administration Always take Itraconazole 130 mg exactly as prescribed by your healthcare provider. ### General Guidelines - Take the capsule **with food** unless your healthcare provider instructs otherwise. - Swallow the capsule whole with water. - Take the medicine at the same time each day. - Complete the entire prescribed course, even if symptoms improve before treatment ends. - The duration of treatment depends on the type and severity of the fungal infection. - Different itraconazole formulations may have different absorption characteristics; use only the product prescribed for you. ### Missed Dose - Take the missed dose as soon as you remember. - If it is almost time for your next scheduled dose, skip the missed dose. - Do not take two doses together. --- # Side Effects Like all medicines, Itraconazole may cause side effects, although not everyone experiences them. ## Common Side Effects - Nausea - Stomach discomfort - Indigestion - Headache - Diarrhea - Constipation - Dizziness ## Less Common Side Effects - Rash - Itching - Elevated liver enzymes - Swelling of the ankles or feet - Fatigue ## Serious Side Effects (Seek Immediate Medical Attention) - Yellowing of the skin or eyes (jaundice) - Severe abdominal pain - Dark-colored urine - Persistent nausea or vomiting - Severe allergic reactions - Difficulty breathing - Swelling of the face, lips, tongue, or throat - Signs of heart failure (shortness of breath, swelling of the legs, rapid weight gain) - Severe skin reactions (rare) --- # Precautions & Warnings Before taking Itraconazole, tell your healthcare provider if you: - Have liver disease. - Have kidney disease. - Have heart failure or a history of heart disease. - Have abnormal heart rhythms. - Are pregnant or planning pregnancy. - Are breastfeeding. - Have previously experienced allergic reactions to azole antifungals. - Are taking multiple prescription medicines. ### Important Warnings - Itraconazole may cause **serious liver injury**. Contact your healthcare provider immediately if you develop jaundice, dark urine, severe fatigue, or persistent nausea. - Itraconazole can **worsen or cause congestive heart failure** and should generally be avoided in patients with ventricular dysfunction unless the benefits outweigh the risks. - Numerous drug interactions can occur because itraconazole strongly affects liver enzymes involved in drug metabolism. - Avoid self-adjusting the dose or stopping treatment early. - Liver function tests may be recommended during prolonged treatment. --- # Drug Interactions Itraconazole has **many clinically important drug interactions** and may interact with: - Statins (e.g., simvastatin, lovastatin) - Certain antiarrhythmic medicines (e.g., quinidine, dofetilide) - Warfarin - Digoxin - Certain benzodiazepines (e.g., midazolam, triazolam) - Calcium channel blockers - Certain immunosuppressants (e.g., tacrolimus, cyclosporine) - Rifampicin and rifabutin (may reduce itraconazole effectiveness) - Phenytoin and carbamazepine - Proton pump inhibitors (PPIs), H2 blockers, and antacids (may reduce absorption of some itraconazole capsule formulations) - Certain HIV medicines - Certain oral diabetes medicines Always provide your healthcare provider with a complete list of all prescription medicines, over-the-counter products, vitamins, and herbal supplements you are taking. --- # Storage Information - Store below **30°C** in a cool, dry place. - Protect from moisture and direct sunlight. - Keep the capsules in their original packaging. - Keep out of the reach of children. - Do not use after the expiry date. --- # Prescription Status **Prescription Only Medicine (Rx)** Itraconazole 130 mg should only be used under the supervision of a qualified healthcare professional. --- # Genuine Medicine Assurance We provide **100% genuine, quality-assured medicines** sourced from authorized pharmaceutical manufacturers and licensed distributors. Every product is stored and handled according to recommended pharmaceutical standards to help ensure its safety, quality, and effectiveness. --- # Frequently Asked Questions (FAQ) ### 1. What is Itraconazole 130 mg used for? Itraconazole 130 mg is used to treat fungal infections of the skin, nails, mouth, and certain internal organs caused by susceptible fungi. ### 2. How does Itraconazole work? Itraconazole blocks the production of ergosterol, an essential component of the fungal cell membrane, preventing fungal growth and eliminating susceptible fungi. ### 3. Should I take Itraconazole with food? Yes. Most itraconazole capsule formulations are recommended to be taken **with food** to improve absorption. Follow the specific instructions provided with your prescribed product. ### 4. How long does Itraconazole take to work? Symptoms may begin improving within **a few days to several weeks**, depending on the infection. Nail infections may take **several months** to appear fully resolved because healthy nails grow slowly. ### 5. Can I stop taking Itraconazole when I feel better? No. Complete the full prescribed course to ensure the infection is fully treated and to reduce the risk of recurrence. ### 6. What are the common side effects? Common side effects include nausea, stomach discomfort, headache, diarrhea, constipation, dizziness, and indigestion. ### 7. Can Itraconazole affect the liver? Yes. Itraconazole can cause liver problems. Contact your healthcare provider immediately if you develop yellowing of the skin or eyes, dark urine, severe fatigue, or persistent nausea. ### 8. Is Itraconazole safe for people with heart failure? Itraconazole may worsen or contribute to **congestive heart failure**. Inform your healthcare provider if you have a history of heart disease or heart failure before starting treatment. ### 9. Can I take antacids while using Itraconazole? Some itraconazole capsule formulations require stomach acid for proper absorption. Antacids, proton pump inhibitors, and H2 blockers may reduce absorption. Follow your healthcare provider's instructions regarding timing or the specific formulation prescribed. ### 10. Is Itraconazole safe during pregnancy? Itraconazole is generally **not recommended during pregnancy** unless the potential benefit outweighs the risk. Women of childbearing potential should discuss appropriate contraception with their healthcare provider during treatment. ### 11. What should I do if I miss a dose? Take the missed dose as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue your regular schedule. Do not take two doses together. ### 12. How should Itraconazole 130 mg be stored? Store below **30°C**, protected from moisture and direct sunlight, in the original packaging and out of the reach of children. ### 13. Why is my fungal nail infection not improving immediately? Even after the fungus is eliminated, healthy nail growth takes time. Visible improvement may require **6–12 months** for toenails and several months for fingernails. ### 14. When should I seek immediate medical attention? Seek emergency medical care if you experience severe allergic reactions, difficulty breathing, swelling of the face or throat, jaundice, severe abdominal pain, signs of heart failure, or severe skin reactions. --- # Medical Disclaimer The information provided on this page is intended for **educational and informational purposes only** and should not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. **Itraconazole 130 mg** should only be used as prescribed by a licensed healthcare professional. Seek immediate medical attention if you experience signs of liver injury, heart failure, severe allergic reactions, or any other serious adverse effects.