COOLGUT

# Mesalazine 1.2 g ## Short Description Mesalazine 1.2 g is an anti-inflammatory medicine primarily used to treat and maintain remission in **ulcerative colitis**, a chronic inflammatory condition affecting the lining of the colon and rectum. It works mainly in the intestine to reduce inflammation and help control symptoms such as diarrhea, rectal bleeding and abdominal discomfort. ## Key Benefits * Helps reduce inflammation in the bowel * Helps control symptoms of ulcerative colitis * Helps maintain remission and reduce recurrence * May help reduce diarrhea and rectal bleeding associated with active disease * Acts locally in the intestinal tract ## Uses / Indications Mesalazine 1.2 g may be prescribed for: * Ulcerative colitis * Active mild to moderate ulcerative colitis * Maintenance of remission in ulcerative colitis * Other inflammatory bowel conditions when specifically prescribed by a doctor ## How It Works Mesalazine, also known as **mesalamine**, is an aminosalicylate anti-inflammatory medicine. It acts mainly on the lining of the intestine to reduce the production and activity of inflammatory substances. This helps decrease inflammation and promote control of bowel symptoms. ## Dosage & Administration * Take Mesalazine 1.2 g exactly as prescribed by your doctor * The dose and treatment duration depend on whether it is being used for an active flare or maintenance treatment * Swallow the tablet whole with water unless your specific product instructions state otherwise * Do not crush, chew or break modified-release or delayed-release tablets unless directed by your doctor * Take it at the same time each day for consistent treatment * Continue treatment for the prescribed duration even if symptoms improve * If you miss a dose, take it when you remember unless it is nearly time for your next dose * Do not take a double dose to make up for a missed dose ## Side Effects Possible side effects may include: * Headache * Nausea * Abdominal pain or discomfort * Indigestion * Diarrhea * Vomiting * Skin rash * Dizziness Contact your doctor promptly if you develop severe abdominal pain, persistent vomiting, worsening diarrhea, unusual bleeding, severe skin reactions, breathing difficulties or symptoms suggesting kidney problems. ## Precautions & Warnings * Inform your doctor if you are allergic to mesalazine, salicylates or any component of the medicine * Tell your doctor if you have kidney or liver problems * Your doctor may recommend kidney function monitoring during treatment * Tell your doctor if you have a history of stomach or intestinal ulcers * Drink adequate fluids unless your doctor has advised you to restrict fluid intake * Report unexplained bruising, bleeding, fever or severe sore throat promptly * Seek medical advice if symptoms of colitis worsen after starting treatment * Use during pregnancy or breastfeeding only after consultation with your doctor * Keep this medicine out of reach of children ## Drug Interactions Tell your doctor or pharmacist about all medicines and supplements you are taking. Mesalazine may require particular caution when used with: * Non-steroidal anti-inflammatory drugs such as ibuprofen or naproxen * Medicines that can affect kidney function * Azathioprine or 6-mercaptopurine * Thioguanine * Other salicylate-containing medicines Your doctor may recommend monitoring depending on the medicines you take and your individual health condition. ## Storage Information * Store at room temperature according to the product label * Keep the medicine in its original packaging * Protect from excessive heat, moisture and direct sunlight * Keep the container tightly closed * Keep out of reach and sight of children * Do not use after the expiry date * Follow the manufacturer's storage instructions for your specific formulation ## Prescription Status Mesalazine 1.2 g is generally a **prescription medicine**. It should be used under the supervision of a qualified healthcare professional, particularly because treatment and monitoring may vary depending on the severity of inflammatory bowel disease. ## Genuine Medicine Assurance * Purchase Mesalazine only from a licensed and reputable pharmacy * Check the product name, strength, batch number, manufacturing details and expiry date * Ensure the packaging and seal are intact * Do not use medicines with damaged, altered or suspicious packaging * Purchase only products from authorized sources * If you suspect that a medicine is counterfeit, consult a pharmacist or contact the appropriate medicine regulatory authority ## Frequently Asked Questions ### What is Mesalazine 1.2 g used for? Mesalazine 1.2 g is mainly used to treat and help maintain remission in ulcerative colitis by reducing inflammation in the bowel. ### Is Mesalazine an antibiotic? No. Mesalazine is an anti-inflammatory medicine and is not an antibiotic. ### Is Mesalazine the same as Mesalamine? Yes. Mesalazine and mesalamine are different names for the same active ingredient. ### How does Mesalazine work? Mesalazine works mainly in the intestinal lining to reduce inflammatory processes that contribute to symptoms of ulcerative colitis. ### Can Mesalazine cure ulcerative colitis? Mesalazine can help control inflammation and maintain remission, but ulcerative colitis is a chronic condition and treatment is generally aimed at controlling symptoms and preventing flare-ups. ### How long does Mesalazine take to work? The time required to improve symptoms varies depending on the severity of the condition and the individual patient. Some people may notice improvement within days, while others may require several weeks. ### Can Mesalazine be taken long term? Yes, mesalazine may be prescribed for long-term maintenance of remission. Regular medical follow-up may be recommended during prolonged treatment. ### Can I stop Mesalazine when I feel better? Do not stop Mesalazine without consulting your doctor. Stopping maintenance treatment may increase the risk of an ulcerative colitis flare. ### Can Mesalazine cause kidney problems? Kidney-related adverse effects are uncommon but possible. Your doctor may recommend kidney function tests, particularly before and during long-term treatment. ### Can Mesalazine be taken during pregnancy? If you are pregnant, planning pregnancy or breastfeeding, consult your doctor before using Mesalazine. Your doctor will assess the benefits and potential risks. ### What should I do if I miss a dose of Mesalazine? Take the missed dose when you remember unless it is nearly time for the next dose. Do not take two doses together unless specifically instructed by your doctor. ### Can Mesalazine be used for Crohn's disease? Mesalazine is primarily used for ulcerative colitis. Its usefulness in Crohn's disease depends on the location and type of disease, so treatment should be determined by a gastroenterologist. ### Can I take painkillers while taking Mesalazine? Some painkillers, particularly NSAIDs such as ibuprofen or naproxen, may require caution because they can affect the kidneys or gastrointestinal tract. Ask your doctor or pharmacist before taking them regularly. ## Medical Disclaimer This information is provided for general educational purposes only and is not a substitute for professional medical advice, diagnosis or treatment. The appropriate dose, formulation and duration of Mesalazine 1.2 g treatment depend on the individual patient's condition and the specific product. Always follow your doctor's instructions and read the product label before use. Seek medical attention if symptoms become severe, worsen unexpectedly or if you experience signs of a serious adverse reaction.