CRISAROL

# Crisaborole 2% Ointment ## Short Description **Crisaborole 2%** is a topical, non-steroidal prescription medicine used on the skin to treat **mild to moderate atopic dermatitis (eczema)**. It is a **phosphodiesterase-4 (PDE-4) inhibitor** formulated for topical application and can be used in appropriate patients according to the product's approved age indication. Crisaborole does not contain a topical corticosteroid, making it a non-steroidal treatment option for eczema. --- ## Key Benefits * Helps treat **mild to moderate atopic dermatitis (eczema)**. * Helps reduce eczema-associated **itching and skin inflammation**. * **Non-steroidal** topical treatment. * Can be used on affected areas of the skin as directed by a healthcare professional. * May provide an alternative to topical corticosteroids for appropriate patients. * Designed for topical use rather than systemic treatment. --- ## Uses / Indications Crisaborole 2% is used for the topical treatment of **mild to moderate atopic dermatitis (eczema)**. Atopic dermatitis may cause: * Dry or scaly skin * Redness * Itching * Skin irritation * Inflammation * Recurring eczema patches Crisaborole should be used only on the skin and according to the instructions provided by the healthcare professional. --- ## How It Works Crisaborole is a **phosphodiesterase-4 (PDE-4) inhibitor**. PDE-4 is an enzyme involved in inflammatory signaling within cells. By inhibiting PDE-4, crisaborole helps regulate inflammatory pathways and reduce the production of inflammatory mediators involved in **atopic dermatitis**. This helps reduce inflammation and the symptoms associated with eczema, including itching and irritation. --- ## Dosage & Administration * Apply a **thin layer of Crisaborole 2% ointment** to affected areas as directed by your doctor. * It is generally applied **twice daily**. * Apply only to the affected skin. * Wash your hands before and after application, unless the hands themselves are being treated. * Avoid contact with the eyes, mouth, and other mucous membranes. * Do not apply inside the nose, mouth, or vagina. * Do not use on areas of skin that have not been affected unless instructed by your healthcare professional. * Continue treatment for the duration recommended by your doctor. ### If You Miss an Application Apply the medicine when you remember. If it is almost time for the next application, skip the missed application and continue with your regular schedule. **Do not apply extra ointment to make up for a missed dose.** --- ## Side Effects ### Common Side Effects The most commonly reported adverse effect of crisaborole is: * **Burning or stinging at the application site** This reaction is usually localized to the area where the medicine is applied. Other possible application-site reactions may include: * Redness * Irritation * Pain or discomfort ### Serious Side Effects Serious allergic reactions are uncommon but can occur. Stop using the medicine and seek medical attention if you develop symptoms such as: * Facial or throat swelling * Severe itching or hives * Difficulty breathing * Severe skin reaction --- ## Precautions & Warnings ### For External Use Only Crisaborole 2% is intended for **topical use only**. Do not swallow the medicine. ### Avoid Eye Contact Avoid getting the ointment in the eyes. If accidental contact occurs, rinse thoroughly with water. ### Allergic Reactions Do not use crisaborole if you have previously experienced a serious allergic reaction to **crisaborole or any component of the formulation**. ### Broken or Infected Skin Tell your healthcare professional if the affected skin is severely damaged, infected, or has open wounds before starting treatment. ### Children Crisaborole has approved pediatric uses, but the minimum approved age can depend on the specific product and regulatory authority. Follow the product label and your healthcare professional's instructions when using it in children. ### Pregnancy Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Your healthcare professional can determine whether crisaborole is appropriate for you. ### Breastfeeding If you are breastfeeding, discuss treatment with your healthcare professional. Avoid applying the medicine directly to the nipple or breast area where the infant could ingest it. --- ## Drug Interactions Because crisaborole is applied to the skin and has relatively limited systemic exposure, **clinically significant drug interactions are not generally expected**. However: * Tell your doctor about all prescription medicines, OTC medicines, vitamins, and supplements you use. * Inform your healthcare professional if you are using other topical medicines on the same area. * Do not combine multiple topical eczema treatments on the same area unless your healthcare professional recommends it. * Using other products simultaneously may increase skin irritation. --- ## Storage Information * Store Crisaborole 2% according to the temperature instructions on the product label. * Keep the container tightly closed when not in use. * Protect the ointment from excessive heat and moisture. * Keep out of direct sunlight. * Keep out of reach of children and pets. * Do not use after the expiration date. * Do not transfer the ointment to another container unless instructed by a pharmacist. --- ## Prescription Status **Crisaborole 2% is a prescription medicine** in the United States and many other markets. It should be used under the guidance of a qualified healthcare professional, particularly when treating children or when eczema symptoms are persistent, severe, infected, or not responding to treatment. --- ## Genuine Medicine Assurance When purchasing Crisaborole 2%: * Purchase only from a **licensed and reputable pharmacy**. * Check the product name, strength, manufacturer, batch/lot number, and expiry date. * Ensure the packaging is intact and properly labeled. * Avoid products from unauthorized or unverified sellers. * Do not use the medicine if the packaging appears tampered with or the product has an unusual appearance. * Retain the original packaging for product verification. **Genuine medicine assurance:** Product authenticity should be verified through the dispensing pharmacy, manufacturer, or relevant national medicines regulatory authority. --- # FAQ – Crisaborole 2% ### 1. What is Crisaborole 2% used for? Crisaborole 2% is a topical non-steroidal medicine used to treat **mild to moderate atopic dermatitis (eczema)**. ### 2. Is Crisaborole 2% a steroid? **No.** Crisaborole is a **non-steroidal PDE-4 inhibitor**. It works by regulating inflammatory signaling in the skin. ### 3. How does Crisaborole 2% work? Crisaborole inhibits the **PDE-4 enzyme**, which helps reduce inflammatory signaling associated with atopic dermatitis. ### 4. How often should Crisaborole 2% be applied? Crisaborole 2% is generally applied as a **thin layer twice daily** to affected areas, or as directed by a healthcare professional. ### 5. Can Crisaborole 2% be used on the face? Yes, crisaborole may be prescribed for eczema affecting the face and other areas of the skin. Avoid contact with the eyes and mucous membranes. ### 6. Can Crisaborole 2% be used for eczema? Yes. Crisaborole is specifically indicated for **mild to moderate atopic dermatitis**, commonly known as eczema. ### 7. Does Crisaborole 2% stop itching? Crisaborole can help reduce the **itching and inflammation associated with atopic dermatitis**. Individual response varies. ### 8. Does Crisaborole 2% contain corticosteroids? No. Crisaborole is a **non-corticosteroid topical treatment**. ### 9. Does Crisaborole cause burning or stinging? Yes. **Application-site burning or stinging** is the most commonly reported adverse reaction. This may occur shortly after application. ### 10. Can Crisaborole 2% be used every day? It can be used regularly as prescribed. The usual regimen is twice-daily application to affected areas. Follow your doctor's instructions regarding the duration of treatment. ### 11. Can Crisaborole 2% be used in children? Yes, crisaborole has approved pediatric uses. However, the approved minimum age varies by product and regulatory jurisdiction. Always follow the specific product label and your pediatrician's instructions. ### 12. Can Crisaborole 2% be used during pregnancy? Tell your healthcare professional if you are pregnant or planning pregnancy. Your doctor can determine whether the expected benefits outweigh any potential risks. ### 13. Can Crisaborole 2% be used while breastfeeding? Discuss its use with your healthcare professional. Avoid applying crisaborole to areas where the nursing infant could directly ingest the medicine. ### 14. Can Crisaborole 2% be used with other eczema creams? It may be possible to use crisaborole with other eczema treatments, but this should be discussed with your healthcare professional. Applying several products to the same area can increase irritation. ### 15. Is Crisaborole 2% suitable for severe eczema? Crisaborole is indicated for **mild to moderate atopic dermatitis**. People with severe or widespread eczema may require other or additional treatments determined by a dermatologist. ### 16. How long does Crisaborole 2% take to work? The response varies between individuals. Continue using it as prescribed and discuss persistent or worsening symptoms with your healthcare professional. ### 17. Can Crisaborole 2% be used on broken skin? Consult your healthcare professional before applying it to severely damaged, open, or infected skin. ### 18. Can Crisaborole 2% cure eczema permanently? Crisaborole can help **control the symptoms and inflammation of atopic dermatitis**, but atopic dermatitis is generally a chronic condition that can have periods of improvement and flare-ups. It is not considered a permanent cure. ### 19. What should I do if I accidentally get Crisaborole in my eyes? Rinse your eyes thoroughly with clean water. If irritation persists or you develop significant symptoms, seek medical advice. ### 20. Is Crisaborole 2% available without a prescription? Crisaborole 2% is generally a **prescription medicine**. Availability and prescription requirements may vary by country. --- ## Medical Disclaimer This information about **Crisaborole 2%** is provided for educational and informational purposes only. It does not replace professional medical advice, diagnosis, or treatment. **Do not start, stop, or change Crisaborole 2% treatment without consulting a qualified healthcare professional.** Follow the specific instructions on your prescribed product, as approved uses, age indications, and labeling may differ between countries. If your eczema becomes severely painful, rapidly worsens, develops pus or extensive crusting, or is accompanied by fever, seek medical evaluation because these symptoms may indicate infection or another condition requiring treatment.