FORTIPLEX

# Cyanocobalamin 4 mcg, Dexpanthenol 3 mg, Nicotinamide 25 mg, Pyridoxine 1 mg, Riboflavin Phosphate 3.5 mg, Thiamine 2.5 mg ## SHORT DESCRIPTION This combination contains several **B-complex vitamins and vitamin-related nutrients**, including thiamine (vitamin B1), riboflavin phosphate (vitamin B2), nicotinamide (vitamin B3), pyridoxine (vitamin B6), cyanocobalamin (vitamin B12), and dexpanthenol (a form of vitamin B5 precursor). These nutrients support normal **energy metabolism, nervous-system function, red blood cell formation, skin health, and overall nutritional requirements**. The combination may be used to prevent or treat deficiencies when dietary intake is inadequate or when increased nutritional requirements are present. ## KEY BENEFITS * Supports normal energy-producing metabolism * Helps maintain healthy nervous-system function * Supports normal red blood cell formation * Helps maintain healthy skin and mucous membranes * Supports normal carbohydrate, protein, and fat metabolism * Helps maintain normal nerve function * Provides multiple B vitamins in a single formulation * May help prevent or correct nutritional deficiencies of the included vitamins ## USES / INDICATIONS This B-complex vitamin combination may be used for: * Prevention or treatment of B-vitamin deficiencies * Nutritional supplementation when dietary intake is inadequate * Increased nutritional requirements * Conditions associated with inadequate intake or absorption of B vitamins * Supportive nutritional therapy during recovery from illness, when recommended by a healthcare professional * Supplementation in individuals at risk of multiple B-vitamin deficiencies The specific indication depends on the formulation, route of administration, patient's nutritional status, and healthcare professional's recommendation. ## HOW IT WORKS Each ingredient contributes to normal body functions: **Thiamine (Vitamin B1):** Helps convert carbohydrates into energy and supports normal nerve and heart function. **Riboflavin Phosphate (Vitamin B2):** Participates in energy metabolism and helps maintain normal skin, mucous membranes, and red blood cells. **Nicotinamide (Vitamin B3):** Supports energy metabolism and contributes to the normal function of the nervous system and skin. **Pyridoxine (Vitamin B6):** Participates in amino-acid metabolism, neurotransmitter production, and normal red blood cell formation. **Cyanocobalamin (Vitamin B12):** Supports DNA synthesis, normal red blood cell formation, and nervous-system function. **Dexpanthenol (Provitamin B5):** Is converted into pantothenic acid, which contributes to the formation of coenzyme A and normal energy and fatty-acid metabolism. Together, these nutrients support several metabolic and physiological processes. ## DOSAGE & ADMINISTRATION The appropriate dose depends on the **specific product formulation, route of administration, age, nutritional status, and medical condition**. * Take or administer exactly as directed by your doctor, pharmacist, or the product label. * Do not exceed the recommended dose. * If the product is an oral formulation, take it according to the manufacturer's instructions. * If it is an injectable preparation, it should be administered only by an appropriately trained healthcare professional. * If a dose is missed, follow the instructions provided for the specific formulation. Do not double the next dose unless specifically instructed. **Important:** The listed quantities should not be interpreted as a recommended daily dose without confirming the product's dosage form and manufacturer's instructions. ## SIDE EFFECTS Most people tolerate B-complex vitamin preparations well when used appropriately. Possible side effects may include: * Nausea * Stomach discomfort * Diarrhea * Headache * Mild dizziness * Skin rash or itching * Injection-site discomfort, if administered by injection Some formulations containing nicotinamide or other B vitamins may cause gastrointestinal symptoms. Seek medical attention if you develop signs of a serious allergic reaction, such as facial swelling, difficulty breathing, severe rash, or severe dizziness. ## PRECAUTIONS & WARNINGS * Do not use this product if you are allergic to any of its ingredients. * Inform your healthcare professional about existing medical conditions and all medicines or supplements you use. * Patients with significant kidney or liver problems should seek medical advice before use. * Avoid taking multiple vitamin or B-complex products simultaneously unless advised by a healthcare professional, as this may result in unnecessary excessive intake. * Long-term excessive intake of vitamin B6 can cause nerve-related problems; use only the recommended amount. * Pregnant or breastfeeding women should consult a healthcare professional before using supplementation. * Injectable formulations should be administered only by qualified healthcare professionals. * Keep all vitamin preparations out of reach of children. ## DRUG INTERACTIONS Potential interactions depend on the dose, formulation, and the patient's other medicines. Important interactions to discuss with a healthcare professional include: * **Levodopa:** Vitamin B6 can reduce the effectiveness of levodopa when levodopa is used without a peripheral dopa-decarboxylase inhibitor. * **Chloramphenicol:** May interfere with the hematologic response to vitamin B12 in some patients. * **Isoniazid and some other medicines:** May affect vitamin B6 status. * **Certain anticonvulsants:** May alter vitamin B6 metabolism. * **Methotrexate and some medicines:** Folate-related interactions are separate from this formulation but should be discussed if taking multiple vitamin preparations. * Other multivitamins or B-complex supplements may increase total vitamin intake. Always inform your doctor or pharmacist about prescription medicines, OTC medicines, vitamins, and herbal supplements you are taking. ## STORAGE INFORMATION * Store according to the manufacturer's recommended temperature and conditions. * Keep in the original packaging until use. * Protect from excessive heat, moisture, and direct sunlight. * Keep out of reach of children. * Do not use after the expiry date. * For injectable preparations, follow the specific storage instructions printed on the packaging. ## PRESCRIPTION STATUS The prescription status depends on the **specific formulation, dosage form, manufacturer, and local regulations**. B-complex vitamin preparations are often available without a prescription when supplied as nutritional supplements or certain oral preparations. Injectable vitamin combinations may be supplied under different regulatory requirements. In Nepal, confirm the current dispensing requirements with a licensed pharmacy or healthcare professional. ## GENUINE MEDICINE ASSURANCE For safe and genuine use: * Purchase the product from a licensed and reputable pharmacy. * Check the product name, ingredients, strength, manufacturer, batch number, and expiry date. * Ensure the packaging and seal are intact. * Do not use products with damaged, altered, or suspicious packaging. * Follow the manufacturer's storage instructions. * If the product is injectable, ensure it is administered by a qualified healthcare professional. * Consult a pharmacist if you have concerns about product authenticity. ## FAQ – FREQUENTLY ASKED QUESTIONS ### 1. What is this B-complex vitamin combination used for? It is used to provide several B vitamins and related nutrients and may help prevent or correct deficiencies when nutritional intake is inadequate or requirements are increased. ### 2. What vitamins are present in this formulation? It contains: * Cyanocobalamin (Vitamin B12) – 4 mcg * Dexpanthenol – 3 mg * Nicotinamide (Vitamin B3) – 25 mg * Pyridoxine (Vitamin B6) – 1 mg * Riboflavin Phosphate (Vitamin B2) – 3.5 mg * Thiamine (Vitamin B1) – 2.5 mg ### 3. What are the benefits of B-complex vitamins? B-complex vitamins support energy metabolism, normal nervous-system function, red blood cell formation, skin health, and other important metabolic processes. ### 4. Does this B-complex combination give energy? The B vitamins are involved in normal energy metabolism. However, they do not act as a stimulant or provide energy in the same way as calories from food. Benefits are most apparent when a deficiency is present. ### 5. Can this product help with vitamin B deficiency? Yes. A healthcare professional may recommend a B-complex preparation to prevent or correct deficiencies depending on the patient's nutritional status and medical needs. ### 6. What is the role of cyanocobalamin in this medicine? Cyanocobalamin is a form of vitamin B12. Vitamin B12 is important for normal red blood cell formation, DNA synthesis, and nervous-system function. ### 7. What is pyridoxine used for? Pyridoxine is vitamin B6. It participates in amino-acid metabolism, neurotransmitter production, and normal blood formation. ### 8. What is nicotinamide? Nicotinamide is a form of vitamin B3. It contributes to normal energy metabolism and supports the normal function of the skin and nervous system. ### 9. What is dexpanthenol? Dexpanthenol is a provitamin form of pantothenic acid (vitamin B5). It is converted in the body to pantothenic acid, which contributes to coenzyme A formation and normal metabolic processes. ### 10. Can B-complex vitamins be taken every day? They can be taken daily when recommended or when the product is intended for daily nutritional supplementation. The appropriate duration and dose depend on the specific product and individual nutritional needs. ### 11. Can I take this product with other multivitamins? Check the ingredients of other supplements before combining them. Taking multiple products containing the same B vitamins may unnecessarily increase total intake. Ask a pharmacist or doctor if you are unsure. ### 12. Are there side effects of B-complex vitamins? Most people tolerate recommended doses well. Possible effects include nausea, stomach discomfort, diarrhea, headache, dizziness, or skin reactions. Excessive intake of certain vitamins, particularly vitamin B6 over prolonged periods, can cause adverse effects. ### 13. Can this B-complex formulation be used during pregnancy? Pregnant or breastfeeding women should consult a healthcare professional before using any vitamin combination, particularly if taking other prenatal or nutritional supplements. ### 14. Is this B-complex vitamin combination available without a prescription? Prescription status varies according to the dosage form, manufacturer, and local regulations. Oral vitamin preparations may be available without a prescription, while injectable formulations may have different requirements. ### 15. Does this medicine treat nerve problems? B vitamins support normal nerve function and may be used to correct nutritional deficiencies that contribute to neurological symptoms. However, not every nerve condition is caused by vitamin deficiency, so persistent symptoms should be evaluated by a healthcare professional. ## MEDICAL DISCLAIMER This information is provided for general educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. The listed ingredients and strengths should be interpreted together with the specific product label and dosage form. Use this vitamin combination according to the manufacturer's instructions or the advice of a qualified healthcare professional. Do not exceed recommended doses or combine multiple vitamin products without professional guidance. Seek medical advice if you have persistent symptoms, significant medical conditions, are pregnant or breastfeeding, or are taking other medicines.