GLIPTIN-M 850MG

# Metformin 850 mg + Sitagliptin Phosphate 50 mg ## Short Description **Metformin 850 mg + Sitagliptin Phosphate 50 mg** is an oral **antidiabetic combination medicine** used for the management of **Type 2 Diabetes Mellitus**. It helps improve blood glucose control when diet and exercise alone are not sufficient. Metformin reduces glucose production by the liver and improves insulin sensitivity, while Sitagliptin helps regulate blood sugar by enhancing the body's natural insulin response after meals. --- # Key Benefits Section - Helps control blood sugar levels in Type 2 diabetes. - Provides dual-action glucose-lowering effects. - Improves insulin sensitivity. - Helps reduce excess glucose production by the liver. - Supports better post-meal blood sugar control. - Helps improve long-term diabetes management. - Lower risk of hypoglycemia compared with some other diabetes medicines when used alone. - Supports better HbA1c control when combined with lifestyle changes. --- # Uses / Indications Metformin 850 mg + Sitagliptin Phosphate 50 mg may be prescribed for: ## Type 2 Diabetes Mellitus Used along with: - Balanced diet. - Regular physical activity. - Lifestyle modifications. It helps improve blood glucose levels in adults with Type 2 diabetes. ## Combination Therapy May be used when: - Metformin alone does not provide adequate blood sugar control. - Additional medication is needed to improve glycemic control. **Note:** This medicine is not used for Type 1 diabetes or diabetic ketoacidosis. --- # How It Works This medicine contains two antidiabetic components: ## Metformin Metformin belongs to the **biguanide** class. It works by: - Reducing glucose production in the liver. - Improving insulin sensitivity. - Increasing glucose uptake by body tissues. - Helping reduce blood sugar levels. ## Sitagliptin Phosphate Sitagliptin belongs to the **DPP-4 inhibitor** class. It works by: - Increasing levels of incretin hormones. - Enhancing insulin release when blood glucose levels are high. - Reducing glucagon release from the pancreas. - Helping control blood sugar after meals. Together, they provide improved glucose control through complementary mechanisms. --- # Dosage & Administration Take **Metformin 850 mg + Sitagliptin Phosphate 50 mg** exactly as prescribed by your doctor. ## General Instructions - Usually taken with meals to reduce stomach-related side effects. - Take at the same time each day. - Swallow the tablet whole with water. - Do not crush or chew unless advised. ## Important Instructions - Continue diet and exercise recommendations. - Monitor blood glucose regularly. - Do not change the dose without medical advice. - Kidney function monitoring may be required. ## Missed Dose - Take the missed dose when remembered. - If it is close to the next dose, skip it. - Do not take double doses. --- # Side Effects ## Common Side Effects - Nausea. - Vomiting. - Diarrhea. - Stomach discomfort. - Gas or bloating. - Loss of appetite. - Headache. - Mild upper respiratory symptoms. ## Less Common Side Effects - Constipation. - Dizziness. - Weakness. ## Serious Side Effects Seek medical attention if you experience: - Severe abdominal pain. - Persistent vomiting. - Signs of pancreatitis (severe stomach pain that may spread to the back). - Severe allergic reaction. - Symptoms of lactic acidosis: - Extreme weakness. - Breathing difficulty. - Unusual tiredness. - Muscle pain. --- # Precautions & Warnings Before taking this medicine, inform your doctor if you have: - Kidney disease. - Liver problems. - Heart failure. - History of pancreatitis. - Alcohol dependence. - Vitamin B12 deficiency. - Severe infection or dehydration. ## Important Warnings - Kidney function should be checked before and during treatment. - Avoid excessive alcohol consumption. - Report severe abdominal pain immediately. - Inform your doctor before surgery or procedures involving contrast dye. - Not recommended for Type 1 diabetes. - Use during pregnancy or breastfeeding only under medical supervision. --- # Drug Interactions Metformin + Sitagliptin may interact with: ## Other Diabetes Medicines Examples: - Insulin. - Sulfonylureas (such as Glimepiride). May increase the risk of low blood sugar. ## Contrast Dyes Used in Imaging Certain contrast agents may affect kidney function and require temporary stopping of Metformin. ## Corticosteroids Examples: - Prednisolone. - Dexamethasone. May increase blood glucose levels. ## Diuretics Some water pills may affect kidney function or blood sugar control. ## Alcohol May increase the risk of lactic acidosis with Metformin. Always inform your doctor about all prescription medicines, supplements, and herbal products you use. --- # Storage Information - Store below **25°C**. - Keep in a cool and dry place. - Protect from moisture and direct sunlight. - Keep tablets in the original packaging. - Keep away from children. - Do not use after the expiry date. --- # Prescription Status **Prescription Only Medicine (Rx)** Metformin 850 mg + Sitagliptin Phosphate 50 mg should be used under the supervision of a qualified healthcare professional with regular blood sugar monitoring. --- # Genuine Medicine Assurance We provide **100% genuine, quality-assured medicines** sourced from licensed pharmaceutical manufacturers and authorized distributors. All medicines are stored and handled according to recommended pharmaceutical standards to maintain their safety, quality, and effectiveness. --- # FAQ Section (Frequently Asked Questions) ## 1. What is Metformin 850 mg + Sitagliptin 50 mg used for? It is used to control blood sugar levels in adults with Type 2 diabetes mellitus. --- ## 2. How does this combination medicine work? Metformin reduces glucose production by the liver, while Sitagliptin improves insulin response and reduces glucose release after meals. --- ## 3. Can this medicine cure diabetes? No. It helps control diabetes but does not cure it. Long-term management includes diet, exercise, and regular monitoring. --- ## 4. Does Sitagliptin cause low blood sugar? Sitagliptin alone has a low risk of hypoglycemia, but the risk may increase when combined with insulin or sulfonylureas. --- ## 5. Should Metformin + Sitagliptin be taken with food? Yes. Taking it with meals may help reduce stomach-related side effects. --- ## 6. Can I stop taking this medicine if my sugar levels improve? No. Do not stop without consulting your doctor because blood sugar may rise again. --- ## 7. Does Metformin cause stomach problems? Yes. Some people may experience nausea, diarrhea, gas, or stomach discomfort, especially when starting treatment. --- ## 8. Can this medicine be used for Type 1 diabetes? No. It is intended for Type 2 diabetes management. --- ## 9. Does Sitagliptin affect the pancreas? Rarely, Sitagliptin may be associated with pancreatitis. Seek medical advice if severe abdominal pain occurs. --- ## 10. Can I drink alcohol while taking this medicine? Avoid excessive alcohol because it may increase the risk of side effects, especially with Metformin. --- ## 11. How long does this medicine take to work? Blood glucose improvement may begin after starting treatment, but full benefits may require several weeks. --- ## 12. What should I do if I miss a dose? Take it when remembered unless it is close to the next dose. Do not double the dose. --- # Medical Disclaimer The information provided on this page is for **educational and informational purposes only** and does not replace professional medical advice, diagnosis, or treatment. **Metformin 850 mg + Sitagliptin Phosphate 50 mg** is a prescription antidiabetic medicine and should only be used under the guidance of a qualified healthcare professional. Always consult your doctor before starting, stopping, or changing any medication. ```