ITRACID -200

# Itraconazole 200 mg ## SHORT DESCRIPTION **Itraconazole 200 mg** is a prescription **triazole antifungal medicine** used to treat various fungal infections. It works by interfering with the production of **ergosterol**, an essential component of fungal cell membranes, thereby inhibiting fungal growth. Itraconazole may be prescribed for fungal infections affecting the skin, nails, mouth, lungs, or other parts of the body. The appropriate dose and treatment duration depend on the type and severity of the infection. ## KEY BENEFITS * Helps treat susceptible fungal infections * May be used for fungal infections of the skin and nails * Can be prescribed for certain oral and systemic fungal infections * Helps inhibit the growth and spread of susceptible fungi * Available in oral formulations for treatment of infections requiring systemic antifungal therapy ## USES / INDICATIONS Itraconazole 200 mg may be prescribed for: * Fungal skin infections such as dermatophytosis * Fungal nail infections (onychomycosis) * Oral candidiasis in selected patients * Vulvovaginal candidiasis in appropriate circumstances * Certain systemic fungal infections * Aspergillosis in selected cases * Histoplasmosis and other susceptible fungal infections **Important:** Itraconazole is not effective against viral or bacterial infections. The approved indications vary according to the formulation and country. ## HOW IT WORKS Itraconazole inhibits the fungal enzyme **lanosterol 14-alpha-demethylase**, which is involved in the production of **ergosterol**. Ergosterol is an important component of the fungal cell membrane. Reducing ergosterol production disrupts the structure and function of the fungal cell membrane, which inhibits fungal growth and can ultimately lead to fungal cell death. ## DOSAGE & ADMINISTRATION * Take Itraconazole 200 mg exactly as prescribed by your doctor. * The dosage and duration depend on the type, location, and severity of the fungal infection. * **Itraconazole capsules should generally be taken immediately after a full meal** to improve absorption. * Swallow capsules whole with water. * Do not crush, chew, or open capsules unless specifically instructed. * Take doses at approximately the same time each day when regular dosing is prescribed. * Complete the prescribed course even if symptoms improve earlier. * Do not take extra doses to compensate for a missed dose. ### Important formulation difference Itraconazole **capsules and oral solution are not interchangeable** because their absorption and dosing instructions can differ. Always follow the instructions for the specific formulation you have been prescribed. ### Missed dose Take the missed dose when remembered unless it is nearly time for the next scheduled dose. Do not take two doses together unless specifically instructed by your doctor. ## SIDE EFFECTS Common side effects may include: * Nausea * Abdominal pain or discomfort * Diarrhea or constipation * Vomiting * Headache * Dizziness * Indigestion * Fatigue * Skin rash ### Serious side effects Seek urgent medical attention if you develop: * Shortness of breath * Swelling of the legs or ankles * Sudden weight gain * Unusual tiredness * Persistent nausea or vomiting * Yellowing of the skin or eyes * Dark urine * Severe abdominal pain * Severe skin rash or blistering * Hearing changes * Signs of a serious allergic reaction Itraconazole can rarely cause **serious liver injury** and has also been associated with **heart failure and other cardiac problems**. ## PRECAUTIONS & WARNINGS ### Liver problems Itraconazole can cause liver injury, including rare cases of serious hepatotoxicity. Tell your doctor if you have liver disease or a history of abnormal liver function. Contact your doctor promptly if you develop: * Loss of appetite * Persistent nausea * Severe fatigue * Dark urine * Pale stools * Yellow skin or eyes * Severe abdominal pain Your doctor may recommend liver-function monitoring during treatment when appropriate. ### Heart failure Itraconazole has been associated with **congestive heart failure** and should be used cautiously or avoided in certain patients with heart failure or significant cardiac disease. Tell your doctor if you have: * Heart failure * Coronary artery disease * Heart rhythm problems * Shortness of breath * Swelling of the legs * Other significant cardiovascular conditions ### Drug absorption Itraconazole capsule absorption can be affected by reduced stomach acidity. Some medicines that reduce stomach acid may decrease itraconazole absorption. ### Pregnancy Itraconazole should generally be used during pregnancy only when clearly indicated by a healthcare professional. Women who could become pregnant should discuss appropriate precautions with their doctor. ### Breastfeeding Itraconazole can pass into breast milk. Tell your doctor if you are breastfeeding before starting treatment. ### Allergies Do not use itraconazole if you have previously experienced a serious allergic reaction to itraconazole or related azole antifungal medicines. ## DRUG INTERACTIONS Itraconazole has **many clinically important drug interactions** because it strongly affects the metabolism of numerous medicines. Tell your doctor or pharmacist about every medicine and supplement you use. Important interactions may involve: * Certain cholesterol-lowering medicines such as **simvastatin and lovastatin** * Certain heart medicines * Some antiarrhythmic medicines * Certain sedatives and sleeping medicines * Some anticoagulants * Certain immunosuppressants * Some anticonvulsants * Certain antibiotics * Some calcium-channel blockers * Certain oral medicines for diabetes * Acid-reducing medicines * Other antifungal medicines Some combinations can cause serious or potentially life-threatening reactions. **Never start a new prescription, OTC medicine, or supplement while taking itraconazole without checking with your doctor or pharmacist.** ## STORAGE INFORMATION * Store Itraconazole 200 mg according to the manufacturer's instructions. * Keep at the recommended room temperature. * Protect from excessive heat, moisture, and direct sunlight. * Keep the medicine in its original packaging. * Keep out of reach and sight of children. * Do not use after the expiry date. * Do not use capsules if the packaging is damaged or the medicine appears abnormal. ## PRESCRIPTION STATUS **Itraconazole 200 mg is a prescription-only antifungal medicine in many countries.** Because itraconazole has important contraindications and numerous drug interactions, treatment should be prescribed and monitored by a qualified healthcare professional. ## GENUINE MEDICINE ASSURANCE To help ensure you receive genuine Itraconazole 200 mg: * Purchase only from a licensed and reputable pharmacy. * Check the medicine name, strength, and dosage form. * Verify the manufacturer's name and product information. * Check the batch number and expiry date. * Ensure the packaging is sealed and undamaged. * Do not use products with altered, incomplete, or suspicious labeling. * Consult a pharmacist if the appearance of the medicine or packaging seems unusual. ## FAQ SECTION ### What is Itraconazole 200 mg used for? Itraconazole 200 mg is an antifungal medicine used to treat various **fungal infections**, including certain infections of the skin, nails, mouth, lungs, and other parts of the body. ### Is Itraconazole 200 mg an antibiotic? No. Itraconazole is an **antifungal medicine**, not an antibacterial antibiotic. It is used against susceptible fungi. ### How does Itraconazole work? Itraconazole blocks an enzyme needed to produce ergosterol, an essential component of fungal cell membranes. This interferes with fungal growth. ### Can Itraconazole 200 mg treat skin fungal infections? Yes. Itraconazole may be prescribed for certain fungal skin infections when a systemic antifungal treatment is appropriate. ### Can Itraconazole treat nail fungus? Yes. Itraconazole is used to treat certain fungal nail infections. Treatment may require a prolonged or pulse-based regimen depending on the affected nails and prescribed treatment plan. ### How should I take Itraconazole 200 mg capsules? Itraconazole capsules are generally taken **immediately after a full meal** and swallowed whole with water. Always follow the instructions supplied with your particular product. ### Can Itraconazole be taken on an empty stomach? Itraconazole capsules are generally absorbed better when taken after a full meal. However, instructions can differ between formulations, so follow your product-specific directions. ### How long does Itraconazole take to work? The time required depends on the type and location of the fungal infection. Symptoms may improve before the infection has been completely cleared, so complete the prescribed treatment. ### Can I stop Itraconazole when symptoms disappear? No. Do not stop treatment early unless your doctor advises you to do so. Fungal infections may require treatment beyond the point when symptoms improve. ### Can Itraconazole cause liver problems? Yes. Itraconazole can cause liver abnormalities and, rarely, serious liver injury. Seek medical advice if you develop jaundice, dark urine, severe fatigue, persistent nausea, or significant abdominal pain. ### Can Itraconazole affect the heart? Yes. Itraconazole has been associated with heart failure and should be used cautiously in patients with certain cardiac conditions. ### Can Itraconazole be taken with other medicines? Itraconazole has **many drug interactions**. Some combinations can be dangerous. Always tell your doctor or pharmacist about all medicines and supplements you take. ### Can Itraconazole be taken with antacids? Some medicines that reduce stomach acidity can affect the absorption of itraconazole capsules. Ask your pharmacist or doctor how to separate or manage these medicines. ### Can Itraconazole be used during pregnancy? Itraconazole should be used during pregnancy only when specifically considered appropriate by a healthcare professional. Tell your doctor if you are pregnant or planning pregnancy. ### Can Itraconazole be taken while breastfeeding? Itraconazole can pass into breast milk. Consult your doctor before taking it while breastfeeding. ### Can I drink alcohol while taking Itraconazole? Because itraconazole can affect the liver, it is advisable to discuss alcohol consumption with your healthcare professional, particularly during prolonged treatment or if you have liver problems. ### What should I do if I miss an Itraconazole dose? Take the missed dose when you remember unless it is nearly time for your next dose. Do not take a double dose to make up for the missed dose. ### Is Itraconazole 200 mg available without a prescription? Itraconazole is generally a **prescription medicine** because of its potential side effects, contraindications, and extensive drug-interaction profile. ### Can Itraconazole treat bacterial infections? No. Itraconazole is specifically an antifungal medicine and does not treat bacterial infections. ### What happens if I take too much Itraconazole? An overdose may increase the risk of adverse effects. Contact a healthcare professional or poison-control service promptly if you have taken more than prescribed. ## MEDICAL DISCLAIMER This information about **Itraconazole 200 mg** is provided for educational and informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Itraconazole has important contraindications, potential liver and cardiac risks, and numerous drug interactions. The correct dosage and treatment duration depend on the type of fungal infection, formulation, medical history, and other medicines being taken. **Do not start, stop, or change Itraconazole 200 mg treatment without consulting a qualified healthcare professional.** Seek urgent medical attention for severe allergic reactions, difficulty breathing, fainting, significant swelling, symptoms of liver injury, or other serious or unusual reactions. Always follow the approved product information and the specific instructions provided by your doctor or pharmacist.