LEFRA 10MG
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LEFRA 10MG TAB 10
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Composition
LEFLUNOMIDE 10 MG
# Leflunomide 10 mg
## Short Description
**Leflunomide 10 mg** is a disease-modifying antirheumatic drug (DMARD) used primarily for the treatment of **rheumatoid arthritis** and other autoimmune inflammatory conditions. It helps reduce joint inflammation, pain, swelling, and slows the progression of joint damage caused by an overactive immune system.
Leflunomide works by regulating immune system activity and reducing the production of inflammatory cells involved in autoimmune diseases.
> **Important:** Leflunomide is a prescription medicine requiring regular medical monitoring, including liver function and blood cell tests.
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# Key Benefits Section
- Helps reduce joint pain and swelling associated with rheumatoid arthritis.
- Slows progression of autoimmune joint damage.
- Improves physical function and mobility.
- Helps control chronic inflammation.
- Reduces stiffness and tenderness of affected joints.
- Supports long-term management of autoimmune arthritis.
- Helps improve quality of life in patients with inflammatory joint diseases.
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# Uses / Indications
Leflunomide 10 mg may be prescribed for:
## Rheumatoid Arthritis (RA)
- Reduces inflammation in joints.
- Helps slow joint damage.
- Improves symptoms such as pain and stiffness.
## Other Autoimmune Conditions
May be prescribed by specialists for certain inflammatory autoimmune disorders based on individual patient needs.
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# How It Works
Leflunomide belongs to the class of medicines called **Disease-Modifying Antirheumatic Drugs (DMARDs).**
It works by:
- Blocking an enzyme called **dihydroorotate dehydrogenase (DHODH)**.
- Reducing the production of activated immune cells (lymphocytes).
- Decreasing abnormal immune system activity.
- Lowering inflammatory responses that damage joints.
Unlike simple pain relievers, Leflunomide helps modify the disease process rather than only reducing symptoms.
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# Dosage & Administration
Take **Leflunomide 10 mg** exactly as prescribed by your doctor.
## General Instructions
- Usually taken once daily.
- Swallow the tablet whole with water.
- May be taken with or without food.
- Take regularly for best results.
- Do not stop treatment without medical advice.
## Treatment Duration
- Leflunomide is generally used as a long-term therapy.
- Improvement may take several weeks to months.
## Missed Dose
- Take the missed dose when remembered.
- If it is close to the next dose, skip it.
- Do not take double doses.
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# Side Effects
## Common Side Effects
- Diarrhea.
- Nausea.
- Stomach discomfort.
- Headache.
- Increased blood pressure.
- Hair thinning or hair loss.
- Skin rash.
- Loss of appetite.
## Serious Side Effects (Seek Medical Attention)
- Liver problems (yellowing of skin/eyes, dark urine).
- Severe infections.
- Unusual bruising or bleeding.
- Low blood cell counts.
- Severe skin reactions.
- Lung problems such as shortness of breath or persistent cough.
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# Precautions & Warnings
Before taking Leflunomide, inform your doctor if you have:
- Liver disease.
- Kidney disease.
- Blood disorders.
- Immune system problems.
- Serious infections.
- Lung disease.
## Important Warnings
- Regular blood tests are required during treatment.
- Avoid pregnancy while taking Leflunomide.
- Women who may become pregnant must use effective contraception.
- Leflunomide can remain in the body for a long time after stopping.
- Avoid excessive alcohol consumption due to liver risk.
- Inform your doctor before receiving vaccines.
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# Drug Interactions
Leflunomide may interact with:
## Immunosuppressive Medicines
Examples:
- Methotrexate.
- Azathioprine.
- Cyclosporine.
May increase the risk of infections or side effects.
## Blood Thinners
Example:
- Warfarin.
May require monitoring of blood clotting levels.
## Liver-Affecting Medicines
Examples:
- Certain antibiotics.
- Some antifungal medicines.
- Other medicines affecting liver function.
May increase liver toxicity risk.
## Vaccines
Live vaccines may not be recommended during treatment.
Always inform your healthcare provider about all prescription medicines, supplements, and herbal products you use.
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# Storage Information
- Store below **25°C**.
- Keep in a cool and dry place.
- Protect from moisture and direct sunlight.
- Keep tablets in the original packaging.
- Keep out of reach of children.
- Do not use after expiry date.
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# Prescription Status
**Prescription Only Medicine (Rx)**
Leflunomide 10 mg should be used only under specialist medical supervision due to possible effects on the liver, blood cells, and immune system.
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# Genuine Medicine Assurance
We provide **100% genuine, quality-assured medicines** sourced from licensed pharmaceutical manufacturers and authorized distributors. All medicines are stored and handled according to recommended pharmaceutical standards to maintain their safety, quality, and effectiveness.
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# FAQ Section (Frequently Asked Questions)
## 1. What is Leflunomide 10 mg used for?
Leflunomide 10 mg is mainly used to treat rheumatoid arthritis by reducing inflammation and slowing joint damage.
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## 2. Is Leflunomide a steroid?
No. Leflunomide is not a steroid. It is a disease-modifying antirheumatic drug (DMARD).
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## 3. How long does Leflunomide take to work?
Leflunomide may take several weeks to months to show its full benefits.
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## 4. Can Leflunomide cure rheumatoid arthritis?
Leflunomide does not cure rheumatoid arthritis but helps control symptoms and slow disease progression.
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## 5. Can Leflunomide be taken daily?
Yes, it is commonly prescribed as a once-daily medicine, but the dose should only be taken as directed by a doctor.
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## 6. Does Leflunomide weaken the immune system?
Yes. Leflunomide reduces excessive immune activity, which may increase susceptibility to infections.
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## 7. Can Leflunomide cause hair loss?
Some patients may experience hair thinning or hair loss, which is usually reversible after medical adjustment.
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## 8. Can pregnant women take Leflunomide?
No. Leflunomide can harm an unborn baby and should not be used during pregnancy unless specifically managed by a specialist.
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## 9. Do I need blood tests while taking Leflunomide?
Yes. Regular monitoring of liver function and blood cell counts is usually required.
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## 10. Can Leflunomide be taken with Methotrexate?
Sometimes they are combined under specialist supervision, but monitoring is required due to increased risks.
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## 11. Can I stop Leflunomide suddenly?
Do not stop without consulting your doctor, as symptoms may worsen.
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## 12. What should I avoid while taking Leflunomide?
Avoid pregnancy, excessive alcohol, and unapproved live vaccines unless advised by your healthcare provider.
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# Medical Disclaimer
The information provided on this page is for **educational and informational purposes only** and does not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. **Leflunomide 10 mg** should be used only under medical supervision with appropriate monitoring for safe and effective treatment.
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