LIPRIL 5MG

# Lisinopril 5 mg ## SHORT DESCRIPTION Lisinopril 5 mg is an **ACE inhibitor (angiotensin-converting enzyme inhibitor)** used to treat high blood pressure and certain heart and kidney conditions. It works by relaxing blood vessels, reducing blood pressure and decreasing the workload on the heart. Lisinopril may be prescribed alone or together with other medicines depending on the patient's condition. ## KEY BENEFITS * Helps lower **high blood pressure (hypertension)** * Helps reduce the workload on the heart * Supports better blood flow by relaxing blood vessels * May help reduce the risk of cardiovascular complications associated with hypertension * Used as part of treatment for **heart failure** * May help protect kidney function in certain patients, particularly those with diabetes and hypertension ## USES / INDICATIONS Lisinopril 5 mg may be prescribed for: * **Hypertension (high blood pressure)** * **Heart failure** * Treatment following certain heart attacks, when clinically appropriate * Reduction of cardiovascular risk in selected patients * Certain kidney-protection strategies in patients with diabetes and hypertension, according to clinical assessment ## HOW IT WORKS Lisinopril blocks the action of an enzyme called **angiotensin-converting enzyme (ACE)**. This reduces the formation of angiotensin II, a substance that normally causes blood vessels to narrow and promotes sodium and water retention. By reducing angiotensin II activity, lisinopril: * Relaxes and widens blood vessels * Lowers blood pressure * Reduces the workload on the heart * Reduces aldosterone-related sodium and water retention ## DOSAGE & ADMINISTRATION * Take Lisinopril 5 mg exactly as prescribed by your doctor. * It is generally taken **once daily**, although the dosage may vary depending on the condition. * It can be taken with or without food. * Take it at approximately the same time each day. * Your doctor may adjust the dose according to blood pressure response, kidney function and other factors. * Do not stop treatment without consulting your doctor. * Blood pressure and kidney function may need to be monitored during treatment. ### Missed Dose Take the missed dose when remembered unless it is close to the next scheduled dose. Do not take two doses together. ## SIDE EFFECTS Common side effects may include: * **Dry cough** * Dizziness * Headache * Fatigue * Low blood pressure * Nausea * Diarrhea * Increased blood potassium levels ### Serious Side Effects Seek immediate medical attention if you develop: * **Swelling of the face, lips, tongue or throat** * Difficulty breathing or swallowing * Severe dizziness or fainting * Significant reduction in urine output * Symptoms of severe high potassium, such as unusual weakness or abnormal heartbeat Swelling caused by an ACE inhibitor is called **angioedema** and can be life-threatening if it affects the airway. ## PRECAUTIONS & WARNINGS * Do not use lisinopril if you have previously experienced **angioedema** associated with an ACE inhibitor. * Tell your doctor if you have kidney disease. * Tell your doctor if you have high blood potassium. * Your kidney function and potassium levels may require monitoring. * Tell your doctor if you are dehydrated or have significant vomiting or diarrhea. * Use cautiously in patients with certain heart or blood-vessel conditions. * Avoid potassium supplements or potassium-containing salt substitutes unless recommended by your doctor. * **Lisinopril should not be used during pregnancy.** Contact your doctor promptly if you become pregnant while taking it. * Tell your doctor if you are breastfeeding. * Rise slowly from sitting or lying positions if you experience dizziness. * Do not stop blood-pressure treatment abruptly without medical advice. ## DRUG INTERACTIONS Lisinopril can interact with several medicines. ### Important Interactions * **Potassium supplements and potassium-containing salt substitutes** — may increase blood potassium. * **Potassium-sparing diuretics** such as spironolactone — may increase the risk of hyperkalemia. * **NSAIDs** such as ibuprofen, naproxen and diclofenac — may reduce the blood-pressure-lowering effect and increase the risk of kidney problems. * **Diuretics** — may increase the risk of low blood pressure, particularly when starting lisinopril. * **Lithium** — lisinopril may increase lithium levels and toxicity risk. * **ARBs or other renin-angiotensin system medicines** — combination may increase the risk of low blood pressure, kidney problems and high potassium. * **Aliskiren** — combination is generally avoided in certain patients, particularly those with diabetes. * **Sacubitril/valsartan** — requires appropriate separation when switching from an ACE inhibitor because of increased angioedema risk. * **SGLT2 inhibitors** — may contribute to additional blood-pressure lowering and require monitoring in some patients. Always tell your doctor or pharmacist about all prescription medicines, over-the-counter medicines, vitamins and herbal supplements you use. ## STORAGE INFORMATION * Store according to the manufacturer's instructions. * Keep tablets in their original packaging. * Store at the recommended room temperature. * Protect from excessive heat, moisture and direct sunlight. * Keep the container tightly closed where applicable. * Keep out of reach of children. * Do not use after the expiry date. * Do not use tablets if the packaging is damaged. ## PRESCRIPTION STATUS **Prescription medicine.** Lisinopril 5 mg should be used under the supervision of a qualified healthcare professional. Prescription requirements may vary by country. ## GENUINE MEDICINE ASSURANCE For safe and genuine Lisinopril 5 mg: * Purchase from a licensed and reputable pharmacy. * Verify the medicine name, strength and manufacturer. * Check the batch number and expiry date. * Ensure the packaging and seal are intact. * Avoid medicines with damaged, altered or suspicious packaging. * Follow the manufacturer's storage instructions. * Consult a pharmacist if you have concerns about medicine authenticity. ## FAQ ### What is Lisinopril 5 mg used for? Lisinopril 5 mg is primarily used to treat **high blood pressure**. It may also be used for heart failure and certain cardiovascular conditions under medical supervision. ### Is Lisinopril a blood pressure medicine? Yes. Lisinopril is an **ACE inhibitor** used to lower blood pressure. ### How does Lisinopril lower blood pressure? It blocks ACE, reducing the production of angiotensin II. This relaxes blood vessels and reduces blood pressure. ### How often should Lisinopril 5 mg be taken? Lisinopril is commonly taken **once daily**, but the exact dose and schedule depend on your condition and your doctor's instructions. ### Can Lisinopril be taken with food? Yes. Lisinopril can generally be taken with or without food. ### Does Lisinopril cause a dry cough? Yes. A persistent **dry cough** is a well-known side effect of ACE inhibitors such as lisinopril. Inform your doctor if the cough becomes troublesome. ### Can Lisinopril cause dizziness? Yes. Dizziness can occur, particularly when starting treatment or after a dose increase. Rise slowly from sitting or lying down. ### Can Lisinopril lower blood pressure too much? Yes. Excessive blood-pressure reduction can cause dizziness, weakness or fainting. Contact your doctor if these symptoms are severe or persistent. ### Can Lisinopril affect the kidneys? Lisinopril can affect kidney function in some patients. Kidney function is commonly monitored, particularly after starting treatment or changing the dose. ### Can Lisinopril increase potassium? Yes. Lisinopril can increase blood potassium levels. Avoid potassium supplements or potassium-containing salt substitutes unless specifically recommended. ### Can I take Lisinopril with Ibuprofen? Ibuprofen and other NSAIDs may reduce the blood-pressure-lowering effect of lisinopril and may increase the risk of kidney problems. Consult your healthcare professional before using NSAIDs regularly. ### Can Lisinopril be taken with Amlodipine? Yes. Lisinopril and amlodipine are sometimes prescribed together because they lower blood pressure through different mechanisms. ### Can Lisinopril be taken with Losartan? Generally, combining an ACE inhibitor such as lisinopril with an ARB such as losartan is **not routinely recommended** because it can increase the risk of kidney problems, high potassium and low blood pressure. ### Can Lisinopril be taken with Hydrochlorothiazide? Yes. Lisinopril may be combined with hydrochlorothiazide when prescribed. The combination can provide additional blood-pressure lowering. ### Can Lisinopril be used during pregnancy? **No. Lisinopril should not be used during pregnancy.** If you become pregnant while taking lisinopril, contact your doctor promptly so your treatment can be reviewed. ### Can Lisinopril be used while breastfeeding? Tell your doctor if you are breastfeeding. Your healthcare professional can determine whether lisinopril is appropriate for your individual situation. ### What is angioedema? Angioedema is sudden swelling, particularly of the face, lips, tongue or throat. It is a rare but potentially life-threatening reaction to ACE inhibitors. Seek emergency medical attention if it occurs. ### What should I do if I miss a dose of Lisinopril? Take the missed dose when remembered unless it is nearly time for the next dose. Do not take a double dose. ### What happens if I take too much Lisinopril? An overdose may cause significant low blood pressure, dizziness, weakness or kidney-related complications. Seek urgent medical attention if you take more than prescribed. ### Can I stop Lisinopril suddenly? Do not stop lisinopril without consulting your doctor. Stopping treatment may allow your blood pressure or underlying heart condition to worsen. ### How should Lisinopril 5 mg be stored? Store Lisinopril 5 mg according to the manufacturer's instructions, generally at room temperature and away from excessive heat and moisture. Keep it in the original packaging and out of reach of children. ## MEDICAL DISCLAIMER This information is provided for educational and informational purposes only and does not replace professional medical advice, diagnosis or treatment. **Lisinopril 5 mg is a prescription ACE inhibitor and should be used under the supervision of a qualified healthcare professional.** Blood pressure, kidney function and potassium levels may require monitoring. Lisinopril can cause serious angioedema and should not be used during pregnancy. Do not start, stop or change the dose without medical advice. Seek urgent medical attention for swelling of the face, lips, tongue or throat or difficulty breathing. Always follow the specific product label and your doctor's instructions.