LOMOHIST PAED.

# DEXTROMETHORPHAN 7.5 MG + PHENYLEPHRINE 5 MG + PROMETHAZINE 1.5 MG ## SHORT DESCRIPTION **Dextromethorphan 7.5 mg + Phenylephrine 5 mg + Promethazine 1.5 mg** is a combination medicine used for the **temporary relief of cough and cold symptoms**. Dextromethorphan helps suppress cough, phenylephrine helps relieve nasal congestion, and promethazine is an antihistamine that can help reduce allergy-related symptoms such as runny nose and sneezing. This combination may cause **drowsiness**, particularly because of promethazine, and should be used according to the product label or a healthcare professional's instructions. --- # KEY BENEFITS * Helps temporarily **reduce coughing**. * Helps relieve **nasal congestion and stuffiness**. * Helps reduce **runny nose and sneezing** associated with colds or allergies. * Provides multiple symptom-relieving actions in a single formulation. * May help improve comfort during common cold and upper-respiratory symptoms. > **Important:** This medicine treats symptoms but does not cure the underlying viral infection causing most common colds. --- # USES / INDICATIONS This combination may be used for temporary relief of: * Dry or irritating cough * Nasal congestion * Runny nose * Sneezing * Cold-related upper respiratory symptoms * Allergy-associated nasal symptoms when appropriate It is generally intended for **short-term symptomatic treatment**. --- # HOW IT WORKS ### Dextromethorphan 7.5 mg Dextromethorphan is a **cough suppressant (antitussive)**. It acts on the cough center in the brain to reduce the urge to cough. ### Phenylephrine 5 mg Phenylephrine is a **decongestant** that stimulates alpha-adrenergic receptors, causing constriction of swollen blood vessels in the nasal passages. This can temporarily reduce: * Nasal swelling * Nasal congestion * Stuffy nose ### Promethazine 1.5 mg Promethazine is an **antihistamine** that blocks histamine H1 receptors. It can help reduce: * Runny nose * Sneezing * Allergy-related symptoms It can also cause **sedation and drowsiness**. ### Combined Action **Dextromethorphan → suppresses cough** **Phenylephrine → reduces nasal congestion** **Promethazine → reduces runny nose/sneezing and may cause sedation** --- # DOSAGE & ADMINISTRATION The correct dose depends on the **specific formulation, patient's age, and product instructions**. ### Administration * Take only the amount recommended on the product label or prescribed by your healthcare professional. * Use an accurate measuring device for liquid formulations. * Do not take more frequently than recommended. * Do not combine with another cough-and-cold product containing the same active ingredients. * Drink adequate fluids unless your doctor has advised fluid restriction. ### Children **Do not give this combination to young children unless specifically directed by a healthcare professional.** Promethazine-containing products can cause serious respiratory depression in susceptible children. Follow the age restrictions and dosing instructions printed on the product packaging. ### Missed Dose If being taken on a regular schedule, take the missed dose when remembered unless it is nearly time for the next dose. **Do not double the dose.** --- # SIDE EFFECTS ## Common Side Effects Possible side effects include: * Drowsiness * Sleepiness * Dizziness * Dry mouth * Blurred vision * Nausea * Stomach discomfort * Headache * Nervousness * Difficulty sleeping * Increased heart rate Phenylephrine may cause **restlessness, palpitations, or increased blood pressure** in some people. ## Serious Side Effects Seek medical attention if you develop: * Difficulty breathing * Severe allergic reaction * Severe confusion * Extreme drowsiness * Rapid or irregular heartbeat * Severe agitation * Seizures * Severe dizziness or fainting --- # PRECAUTIONS & WARNINGS ## Drowsiness Promethazine can cause significant drowsiness. Avoid driving, operating machinery, or performing hazardous activities until you know how the medicine affects you. ## Alcohol **Avoid alcohol** while taking this medicine. Alcohol can increase the sedative effects of promethazine and may worsen dizziness, impaired coordination, and respiratory depression. ## High Blood Pressure Phenylephrine can increase blood pressure and heart rate. Consult a healthcare professional before use if you have: * Hypertension * Heart disease * Arrhythmias * Hyperthyroidism ## Glaucoma Promethazine may worsen certain types of glaucoma. Inform your healthcare professional if you have glaucoma or increased eye pressure. ## Urinary Retention Promethazine may worsen difficulty urinating, particularly in people with an enlarged prostate or urinary obstruction. ## Respiratory Conditions Promethazine can cause respiratory depression, especially in susceptible individuals. Use cautiously and only under professional advice if you have: * Asthma * Chronic respiratory disease * Sleep apnea * Breathing difficulties ## Children Promethazine can cause serious and potentially fatal respiratory depression in very young children. Do not administer promethazine-containing products to children below the age specified on the product labeling. ## Persistent Cough Seek medical evaluation if the cough: * Lasts more than a few weeks * Produces blood * Is accompanied by significant breathing difficulty * Is associated with persistent fever * Is associated with chest pain ## Pregnancy Tell your healthcare professional if you are pregnant or planning pregnancy. The combination should be used during pregnancy only when considered appropriate by a healthcare professional. ## Breastfeeding Consult a healthcare professional before using this medicine while breastfeeding. Promethazine and other ingredients may affect the infant or milk production. --- # DRUG INTERACTIONS ### MAO Inhibitors Do not use dextromethorphan with **monoamine oxidase inhibitors (MAOIs)** or within the recommended washout period after stopping an MAOI, because serious interactions may occur. ### SSRIs and Other Serotonergic Medicines Dextromethorphan can interact with medicines that increase serotonin, including some: * Antidepressants * SSRIs * SNRIs * Tricyclic antidepressants * Other serotonergic medicines This may increase the risk of **serotonin syndrome**. ### Sedatives and CNS Depressants Promethazine can increase sedation when combined with: * Benzodiazepines * Sleeping medicines * Opioids * Sedating antihistamines * Certain antipsychotics * Other CNS depressants ### Alcohol Alcohol can significantly increase drowsiness and impairment. ### Blood Pressure Medicines Phenylephrine may affect blood pressure and can interact with certain medicines used to treat hypertension or cardiovascular disease. ### Other Cough and Cold Medicines Avoid taking multiple products containing: * Dextromethorphan * Phenylephrine * Promethazine * Other antihistamines * Other decongestants unless specifically advised by a healthcare professional. --- # STORAGE INFORMATION * Store according to the manufacturer's instructions. * Keep the container tightly closed. * Protect from excessive heat, moisture, and direct sunlight. * Keep out of reach of children. * Use the supplied measuring device for liquid formulations. * Do not use after the expiry date. * Do not use if the packaging is damaged or the product has changed significantly in appearance. --- # PRESCRIPTION STATUS **Prescription status varies by country and formulation.** Products containing **promethazine, dextromethorphan, or phenylephrine** may be available OTC in some regions but may be prescription-only or subject to additional restrictions elsewhere. Always follow local regulations and the product label. --- # GENUINE MEDICINE ASSURANCE When purchasing **Dextromethorphan + Phenylephrine + Promethazine**, obtain it from a **licensed pharmacy or authorized medicine supplier**. Check the product for: * Correct active ingredients and strengths * Manufacturer information * Batch/lot number * Manufacturing and expiry dates * Intact packaging and seal * Regulatory labeling * Patient information leaflet Do not use products with damaged packaging, altered labels, missing batch information, or questionable authenticity. --- # FAQ – DEXTROMETHORPHAN + PHENYLEPHRINE + PROMETHAZINE ### 1. What is Dextromethorphan 7.5 mg + Phenylephrine 5 mg + Promethazine 1.5 mg used for? It is used for temporary relief of **cough, nasal congestion, runny nose, and sneezing** associated with colds or allergies. ### 2. What does Dextromethorphan do? Dextromethorphan is a **cough suppressant** that reduces the urge to cough. ### 3. What does Phenylephrine do? Phenylephrine is a **nasal decongestant** that reduces swelling inside the nasal passages and helps relieve a blocked nose. ### 4. What does Promethazine do? Promethazine is an antihistamine that can reduce **runny nose and sneezing** and may cause drowsiness. ### 5. Does this medicine cure a cold? No. It provides **symptomatic relief** but does not eliminate the viruses that commonly cause colds. ### 6. Does this medicine cause sleepiness? Yes. Promethazine can cause significant **drowsiness and sedation**. ### 7. Can I drive after taking this medicine? Avoid driving or operating machinery until you know how it affects you. Promethazine may impair alertness and coordination. ### 8. Can I drink alcohol while taking this medicine? It is best to **avoid alcohol** because it can significantly increase drowsiness and central nervous system depression. ### 9. Can I take this medicine for a dry cough? Dextromethorphan is particularly useful for suppressing a **dry or irritating cough**. However, persistent or unexplained cough should be evaluated medically. ### 10. Can this medicine be used for a blocked nose? Yes. Phenylephrine is included to provide temporary relief from **nasal congestion**. ### 11. Can people with high blood pressure take this medicine? Phenylephrine can raise blood pressure. People with hypertension should consult a healthcare professional before using it. ### 12. Can children take this medicine? Children should only receive this product according to the **specific product labeling and professional medical advice**. Promethazine can cause serious respiratory depression in young children. ### 13. Can I take this medicine with antidepressants? Some antidepressants can interact with dextromethorphan and increase the risk of **serotonin syndrome**. Check with a doctor or pharmacist before combining them. ### 14. Can I take this medicine with an MAOI? Dextromethorphan should not be combined with MAO inhibitors and should generally be avoided during the appropriate period after MAOI treatment. ### 15. Can I take another cold medicine at the same time? Do not combine multiple cough-and-cold products without checking their ingredients. You could accidentally take excessive amounts of **dextromethorphan, phenylephrine, or antihistamines**. ### 16. What are common side effects of this medicine? Common effects include **drowsiness, dizziness, dry mouth, nausea, headache, and nervousness**. ### 17. Can this medicine increase blood pressure? Yes. Phenylephrine can increase blood pressure and heart rate in some individuals. ### 18. How long should I use this medicine? Use it for the **shortest period necessary** to control symptoms and follow the product instructions. Seek medical advice if symptoms persist or worsen. ### 19. Can I take this medicine during pregnancy? Consult your healthcare professional before use during pregnancy. The combination should only be used when medically appropriate. ### 20. When should I see a doctor for a cough? Seek medical attention for a cough accompanied by **difficulty breathing, chest pain, coughing blood, persistent high fever, severe weakness, or significant worsening**, or for a cough that does not improve as expected. --- # MEDICAL DISCLAIMER This information about **Dextromethorphan 7.5 mg + Phenylephrine 5 mg + Promethazine 1.5 mg** is provided for general educational purposes only and does not replace professional medical advice, diagnosis, or treatment. This medicine is intended for **symptomatic relief** and does not treat the underlying cause of most viral respiratory infections. Promethazine may cause significant sedation and respiratory depression, while phenylephrine can increase blood pressure and heart rate. Dextromethorphan can interact with serotonergic medicines and MAO inhibitors. **Avoid alcohol and do not drive or operate machinery if you are drowsy or impaired.** Do not give this medicine to young children unless specifically permitted by the product labeling and directed by a healthcare professional. Seek medical attention for severe breathing difficulty, chest pain, severe allergic reactions, confusion, or a persistent/worsening cough. **Use only according to the product label or directions provided by a qualified healthcare professional.**