MEFTAL SPAS

# DICYCLOMINE 10 MG + MEFENAMIC ACID 250 MG ## SHORT DESCRIPTION **Dicyclomine 10 mg + Mefenamic Acid 250 mg** is a combination medicine used for the short-term relief of **pain associated with abdominal cramps and spasms**, including certain types of menstrual pain. Dicyclomine is an **antispasmodic** that relaxes intestinal smooth muscle, while mefenamic acid is a **non-steroidal anti-inflammatory drug (NSAID)** that reduces pain and inflammation. This combination addresses both **muscle spasms and pain/inflammation**. --- ## KEY BENEFITS * Helps relieve **abdominal pain and cramping** associated with spasms. * Helps reduce **menstrual (period) pain** when prescribed for this purpose. * Dicyclomine helps relax intestinal smooth muscle. * Mefenamic acid helps reduce pain and inflammation. * Provides complementary relief when pain involves both **spasms and inflammation**. * May reduce cramping-related discomfort during painful periods. --- ## USES / INDICATIONS Dicyclomine + Mefenamic Acid may be prescribed for: 1. **Abdominal cramps and spasmodic pain** 2. **Menstrual cramps (dysmenorrhea)** 3. Pain associated with intestinal smooth-muscle spasms 4. Other short-term painful cramping conditions when specifically prescribed The exact approved uses depend on the product formulation and local regulations. > **Important:** Severe, unexplained, persistent, or worsening abdominal pain should be medically evaluated rather than treated repeatedly with an antispasmodic/NSAID combination. --- ## HOW IT WORKS ### Dicyclomine Dicyclomine is an **anticholinergic antispasmodic**. It reduces abnormal contractions of smooth muscle in the gastrointestinal tract, helping relax intestinal muscles and reduce **cramping and spasms**. ### Mefenamic Acid Mefenamic acid is an **NSAID**. It inhibits cyclooxygenase (COX) enzymes and reduces the production of **prostaglandins**, chemical mediators involved in pain and inflammation. During menstruation, reduced prostaglandin activity can help decrease uterine contractions and menstrual pain. ### Combination Effect The two ingredients work through different mechanisms: **Dicyclomine → reduces spasms** **Mefenamic acid → reduces pain and inflammation** --- ## DOSAGE & ADMINISTRATION ### Typical Adult Use The exact dose should follow the **product label and healthcare professional's prescription**. Because this is a combination product containing an NSAID, it is generally intended for **short-term use at the lowest effective dose**. ### How to Take * Take exactly as directed. * Mefenamic acid is generally best taken **with or after food** to reduce stomach irritation. * Swallow the tablet with water. * Do not exceed the recommended dose. * Do not use for longer than advised without medical review. ### During Menstrual Pain If prescribed for dysmenorrhea, treatment is generally started around the beginning of menstrual pain and continued only for the duration recommended by the healthcare professional. ### Missed Dose Take the missed dose when remembered unless it is close to the next scheduled dose. **Do not double the dose.** --- ## SIDE EFFECTS ### Common Side Effects Possible side effects include: * Nausea * Vomiting * Indigestion * Stomach discomfort * Diarrhea or constipation * Dizziness * Headache * Dry mouth * Blurred vision * Drowsiness * Increased heart rate ### Dicyclomine-Related Effects Because dicyclomine has anticholinergic effects, it may cause: * Dry mouth * Blurred vision * Constipation * Difficulty urinating * Reduced sweating * Fast heartbeat * Drowsiness or dizziness ### Mefenamic Acid-Related Effects Mefenamic acid may cause: * Stomach irritation * Heartburn * Nausea * Indigestion * Diarrhea Rare but serious NSAID-related effects include **stomach ulcers, gastrointestinal bleeding, kidney injury, severe allergic reactions, and cardiovascular events**. ### Seek Medical Attention Immediately For * Vomiting blood * Black or tarry stools * Severe abdominal pain * Difficulty breathing * Facial or throat swelling * Severe skin rash or blistering * Chest pain * Sudden weakness or speech difficulty * Markedly reduced urination --- ## PRECAUTIONS & WARNINGS ### Stomach Ulcers and Bleeding Mefenamic acid can increase the risk of **stomach or intestinal ulcers and bleeding**. Tell your healthcare professional if you have: * Previous stomach ulcers * Gastrointestinal bleeding * Severe gastritis * Inflammatory bowel disease ### Kidney Disease NSAIDs can reduce kidney blood flow and may worsen kidney function. Use only under medical supervision if you have kidney disease, dehydration, or significant heart disease. ### Heart Disease and Blood Pressure NSAIDs may increase blood pressure and can increase cardiovascular risk, particularly with prolonged use or in people with cardiovascular disease. ### Liver Disease Tell your healthcare professional if you have liver disease. ### Asthma Some people with asthma may experience worsening symptoms or allergic reactions with NSAIDs, particularly those with a history of NSAID-sensitive asthma. ### Anticholinergic Effects Dicyclomine should be used cautiously in people with: * Glaucoma, particularly angle-closure glaucoma * Urinary retention or enlarged prostate * Gastrointestinal obstruction * Severe ulcerative colitis * Certain heart rhythm problems ### Heat Exposure Dicyclomine can reduce sweating. Use caution in hot environments because this may increase the risk of **overheating or heat-related illness**. ### Driving and Machinery Dizziness, blurred vision, or drowsiness may occur. Avoid driving or operating machinery until you know how the medicine affects you. ### Pregnancy Mefenamic acid should generally be **avoided during pregnancy unless specifically prescribed**, and NSAIDs are particularly concerning later in pregnancy. Tell your healthcare professional if you are pregnant or planning pregnancy. ### Breastfeeding Discuss use with a healthcare professional before breastfeeding, particularly because this combination contains both an NSAID and an anticholinergic medicine. ### Older Adults Older adults may be more susceptible to NSAID-related gastrointestinal, kidney, cardiovascular, and anticholinergic adverse effects. --- ## DRUG INTERACTIONS ### Other NSAIDs Do not routinely combine mefenamic acid with other NSAIDs such as: * Ibuprofen * Naproxen * Diclofenac * Aspirin at analgesic/anti-inflammatory doses Combining NSAIDs increases the risk of **stomach bleeding, kidney problems, and other adverse effects**. ### Anticoagulants Medicines such as **warfarin** and certain direct oral anticoagulants can increase bleeding risk when combined with NSAIDs. ### Antiplatelet Medicines Aspirin and other antiplatelet medicines may increase gastrointestinal bleeding risk. ### Corticosteroids Medicines such as prednisolone can increase the risk of gastrointestinal ulceration and bleeding when combined with NSAIDs. ### ACE Inhibitors / ARBs / Diuretics NSAIDs can reduce the effectiveness of some blood-pressure medicines and may increase the risk of kidney problems when combined with: * ACE inhibitors * ARBs * Diuretics ### Lithium NSAIDs can increase lithium levels and potentially increase lithium toxicity. ### Methotrexate NSAIDs may increase methotrexate exposure and toxicity in some situations. ### Anticholinergic Medicines Other medicines with anticholinergic effects may increase dicyclomine-related side effects such as dry mouth, constipation, blurred vision, urinary retention, and rapid heartbeat. ### Alcohol Alcohol can increase stomach irritation and bleeding risk associated with NSAIDs and may worsen dizziness or drowsiness. Always provide your healthcare professional with a complete list of medicines, supplements, and herbal products you use. --- ## STORAGE INFORMATION * Store according to the manufacturer's instructions. * Keep at room temperature unless otherwise specified. * Protect from excessive heat, moisture, and direct sunlight. * Keep the medicine in its original packaging. * Keep out of reach and sight of children. * Do not use after the expiry date. * Do not use tablets if the packaging is damaged. --- ## PRESCRIPTION STATUS **Prescription status varies by country and product formulation.** Dicyclomine + Mefenamic Acid may be prescription-only in some regions and subject to different dispensing regulations elsewhere. Because the product contains **mefenamic acid, an NSAID**, prolonged or unsupervised use is not recommended. --- ## GENUINE MEDICINE ASSURANCE When purchasing **Dicyclomine 10 mg + Mefenamic Acid 250 mg**, obtain it from a **licensed pharmacy or authorized medicine supplier**. Before using the product, verify: * Medicine name and strength * Active ingredients * Manufacturer * Batch/lot number * Manufacturing and expiry dates * Packaging and seal integrity * Regulatory information * Tablet appearance Avoid medicines with damaged packaging, missing labels, altered expiry dates, or questionable authenticity. --- # FAQ – DICYCLOMINE 10 MG + MEFENAMIC ACID 250 MG ### 1. What is Dicyclomine 10 mg + Mefenamic Acid 250 mg used for? It is used for short-term relief of **painful abdominal cramps and spasms** and may also be prescribed for **menstrual cramps**. ### 2. How does Dicyclomine + Mefenamic Acid work? Dicyclomine relaxes intestinal smooth muscle to reduce spasms, while mefenamic acid reduces prostaglandin production to relieve pain and inflammation. ### 3. Can this medicine be used for period pain? Yes. Mefenamic acid is commonly used for **dysmenorrhea (painful periods)**, and the dicyclomine component may help when cramping or spasms are prominent. ### 4. Should I take Dicyclomine + Mefenamic Acid with food? Mefenamic acid is generally better tolerated when taken **with or after food**, unless your healthcare professional gives different instructions. ### 5. Can Dicyclomine + Mefenamic Acid be taken every day? It should generally be used for the **shortest duration necessary**. Long-term or frequent use should be discussed with a healthcare professional. ### 6. Can this medicine cause stomach problems? Yes. Mefenamic acid can cause indigestion, stomach pain, nausea, ulcers, and, rarely, gastrointestinal bleeding. ### 7. Can I take ibuprofen with this medicine? Generally, avoid combining mefenamic acid with ibuprofen or other NSAIDs unless specifically instructed by a healthcare professional because this can increase the risk of adverse effects and bleeding. ### 8. Can Dicyclomine cause dry mouth? Yes. **Dry mouth is a common anticholinergic effect** of dicyclomine. ### 9. Can Dicyclomine cause blurred vision? Yes. Dicyclomine may cause blurred vision. Avoid driving if your vision or alertness is affected. ### 10. Can this medicine cause constipation? Yes. Dicyclomine can reduce intestinal movement and may cause **constipation**. ### 11. Can I drink alcohol while taking this medicine? It is advisable to avoid or limit alcohol because it may increase stomach irritation and bleeding risk from mefenamic acid and may worsen dizziness or drowsiness. ### 12. Can I take this medicine during pregnancy? Consult your healthcare professional before use. **Mefenamic acid and other NSAIDs may pose pregnancy-related risks**, particularly later in pregnancy. ### 13. Can I take Dicyclomine + Mefenamic Acid while breastfeeding? Discuss its use with your healthcare professional before breastfeeding. ### 14. What happens if I miss a dose? Take it when remembered unless it is nearly time for your next dose. **Do not double the dose.** ### 15. Can this medicine treat unexplained abdominal pain? It may relieve symptoms but does not necessarily treat the underlying cause. Persistent, severe, or unexplained abdominal pain should be medically evaluated. ### 16. What are the warning signs of stomach bleeding? Warning signs include **vomiting blood, black/tarry stools, bloody stools, severe abdominal pain, weakness, or fainting**. Seek urgent medical attention if these occur. ### 17. Can people with kidney disease take this medicine? Mefenamic acid can affect kidney function. People with kidney disease should only use it after appropriate medical evaluation. ### 18. Can people with asthma take Mefenamic Acid? Some people with asthma can have NSAID-triggered bronchospasm. Tell your healthcare professional if you have asthma or have previously reacted to aspirin or other NSAIDs. ### 19. Is Dicyclomine + Mefenamic Acid available without a prescription? Prescription requirements vary by country. Because the combination contains an NSAID and an anticholinergic medicine, professional guidance is recommended. ### 20. What should I do if my abdominal pain becomes severe? Do not simply continue taking painkillers. **Severe, sudden, persistent, or worsening abdominal pain**, especially with fever, repeated vomiting, blood in the stool, fainting, or abdominal swelling, requires prompt medical evaluation. --- ## MEDICAL DISCLAIMER This information about **Dicyclomine 10 mg + Mefenamic Acid 250 mg** is provided for general educational purposes only and does not replace professional medical advice, diagnosis, or treatment. Mefenamic acid is an NSAID that can cause **gastrointestinal bleeding, ulcers, kidney problems, cardiovascular effects, and serious allergic reactions** in susceptible individuals. Dicyclomine can cause anticholinergic effects such as dry mouth, blurred vision, constipation, urinary retention, and increased heart rate. Do not combine this medicine with other NSAIDs unless specifically instructed by a healthcare professional. Seek urgent medical attention for **vomiting blood, black stools, severe abdominal pain, difficulty breathing, facial swelling, chest pain, or other serious symptoms**. Always follow the **specific product labeling and your healthcare professional's instructions** regarding dosage, duration, contraindications, and drug interactions.