METRO-400

# Metronidazole 400 mg ## Short Description **Metronidazole 400 mg** is a **prescription antimicrobial medicine** belonging to the nitroimidazole group. It is used to treat a wide range of **bacterial and parasitic infections**, including infections caused by anaerobic bacteria and certain protozoa. Metronidazole works by damaging the DNA of susceptible microorganisms, stopping their growth and helping eliminate the infection. It is commonly used for infections of the digestive system, reproductive system, dental infections, and other body tissues. --- # Key Benefits Section - Effective against anaerobic bacterial infections. - Treats certain parasitic infections caused by protozoa. - Helps manage infections of the stomach, intestine, and reproductive tract. - Useful in treating dental and gum infections caused by susceptible bacteria. - Helps reduce infection-related symptoms such as pain, swelling, and discharge. - Provides targeted antimicrobial action when prescribed appropriately. - Available in oral dosage form for convenient administration. - Helps prevent complications when infections are treated correctly. --- # Uses / Indications Metronidazole 400 mg is indicated for the treatment of infections caused by susceptible bacteria and parasites, including: ### Bacterial Infections - Anaerobic bacterial infections - Dental infections and gum infections - Pelvic infections - Abdominal infections - Certain skin and soft tissue infections - Infections after surgery caused by anaerobic bacteria ### Protozoal Infections - Amoebiasis (intestinal and liver infection caused by *Entamoeba histolytica*) - Giardiasis - Trichomoniasis ### Other Uses - Treatment of certain vaginal infections such as bacterial vaginosis - Prevention of certain surgical infections when prescribed > **Note:** Metronidazole does not treat viral infections such as common cold or flu. --- # How It Works Metronidazole is a **nitroimidazole antimicrobial agent**. It works by: - Entering susceptible bacterial and protozoal cells. - Being converted into active metabolites inside microorganisms. - Damaging microbial DNA. - Preventing DNA replication and protein production. - Causing death of the infectious organism. This action helps eliminate anaerobic bacteria and certain parasites responsible for infection. --- # Dosage & Administration Always take Metronidazole 400 mg exactly as prescribed by your healthcare provider. ### General Guidelines - Take orally with water. - May be taken with or after food to reduce stomach upset. - Swallow tablets whole unless instructed otherwise. - Take doses at evenly spaced times. - Complete the full course even if symptoms improve. - Do not stop treatment early unless advised by your doctor. ### Missed Dose - Take the missed dose as soon as you remember. - If it is close to your next dose, skip the missed dose. - Do not take two doses together. ### Important Advice - Avoid alcohol during treatment and for at least **48–72 hours after completing therapy**, as it may cause unpleasant reactions. - Follow hygiene measures to reduce reinfection when treating certain infections. --- # Side Effects Like all medicines, Metronidazole may cause side effects. ## Common Side Effects - Nausea - Vomiting - Stomach discomfort - Diarrhea - Loss of appetite - Metallic taste in the mouth - Headache - Dizziness ## Less Common Side Effects - Dark-colored urine - Dry mouth - Skin rash - Fatigue - Mouth irritation ## Serious Side Effects (Seek Immediate Medical Attention) - Severe allergic reactions - Seizures - Numbness or tingling of hands and feet (peripheral neuropathy) - Severe skin reactions - Confusion or unusual neurological symptoms - Persistent severe diarrhea --- # Precautions & Warnings Before taking Metronidazole, inform your healthcare provider if you: - Have liver disease. - Have kidney problems. - Have a history of neurological disorders. - Have blood disorders. - Are pregnant or planning pregnancy. - Are breastfeeding. - Have a history of allergic reactions to nitroimidazole medicines. - Are taking blood-thinning medicines. ### Important Warnings - Avoid alcohol during treatment and for at least 48–72 hours after the last dose. - Complete the prescribed course to prevent treatment failure and resistance. - Prolonged use may increase the risk of nerve-related side effects. - Seek medical advice if numbness, tingling, or weakness develops. - Use caution in patients with severe liver impairment. - Do not use for infections caused by viruses. --- # Drug Interactions Metronidazole may interact with: - **Warfarin and other anticoagulants** (may increase bleeding risk) - **Alcohol** (may cause flushing, nausea, vomiting, and rapid heartbeat) - **Lithium** (may increase lithium levels) - **Disulfiram** (may cause mental health-related reactions) - **Phenytoin** - **Phenobarbital** - Certain chemotherapy medicines - Other medicines affecting liver metabolism Always inform your healthcare provider about all prescription medicines, over-the-counter medicines, vitamins, and herbal supplements you are taking. --- # Storage Information - Store below **30°C** in a cool, dry place. - Protect from moisture and direct sunlight. - Keep tablets in the original packaging. - Keep out of reach of children. - Do not use after the expiry date. --- # Prescription Status **Prescription Only Medicine (Rx)** Metronidazole 400 mg should be used under the guidance of a qualified healthcare professional. --- # Genuine Medicine Assurance We provide **100% genuine, quality-assured medicines** sourced from authorized pharmaceutical manufacturers and licensed distributors. Every product is stored and handled according to recommended pharmaceutical standards to help ensure its safety, quality, and effectiveness. --- # Frequently Asked Questions (FAQ) ## 1. What is Metronidazole 400 mg used for? Metronidazole 400 mg is used to treat bacterial infections caused by anaerobic bacteria and certain parasitic infections such as amoebiasis, giardiasis, and trichomoniasis. ## 2. How does Metronidazole work? It damages the DNA of susceptible bacteria and parasites, preventing them from growing and causing infection. ## 3. Can Metronidazole treat stomach infections? Yes. It may be used for certain intestinal infections, including amoebiasis and infections caused by anaerobic bacteria. ## 4. Should I take Metronidazole with food? Taking it with or after food may help reduce stomach discomfort. ## 5. Can I drink alcohol while taking Metronidazole? No. Avoid alcohol during treatment and for at least 48–72 hours after finishing the medicine because it may cause unpleasant reactions. ## 6. How long does Metronidazole take to work? Symptoms may begin improving within a few days, but the full course must be completed for effective treatment. ## 7. Can I stop Metronidazole when I feel better? No. Stopping early may allow the infection to return and may contribute to antibiotic resistance. ## 8. Does Metronidazole cause a metallic taste? Yes. A metallic taste is a common side effect and usually disappears after treatment ends. ## 9. Can Metronidazole be used during pregnancy? Metronidazole may be used during pregnancy when prescribed by a healthcare provider after evaluating benefits and risks. ## 10. Can Metronidazole treat viral infections? No. Metronidazole does not work against viruses such as influenza or common cold viruses. ## 11. What should I do if I miss a dose? Take the missed dose when you remember unless it is near the next scheduled dose. Do not double the dose. ## 12. Can Metronidazole cause diarrhea? Yes. Mild diarrhea can occur. Seek medical advice if diarrhea is severe, persistent, or contains blood. ## 13. Does Metronidazole cause drowsiness? Some people may experience dizziness or tiredness. Avoid driving if you feel affected. ## 14. When should I seek medical help? Seek immediate medical attention for severe allergic reactions, seizures, numbness or tingling, severe skin reactions, or unusual neurological symptoms. --- # Medical Disclaimer The information provided on this page is intended for **educational and informational purposes only** and should not replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before starting, stopping, or changing any medication. **Metronidazole 400 mg** should only be used as prescribed by a licensed healthcare professional. Seek immediate medical attention if you experience severe side effects, allergic reactions, or serious symptoms. ```