SELOKEN XL 100MG

# METOPROLOL TARTRATE 100 MG ## SHORT DESCRIPTION **Metoprolol Tartrate 100 mg** is a **beta-1 selective beta-blocker** used to treat high blood pressure, certain heart rhythm disorders, angina (chest pain), and other cardiovascular conditions. It works mainly by slowing the heart rate and reducing the force with which the heart pumps, thereby lowering blood pressure and reducing the heart's oxygen demand. Metoprolol tartrate is an **immediate-release formulation** and may require more frequent dosing than extended-release metoprolol formulations. ## KEY BENEFITS * Helps lower **high blood pressure**. * Slows a fast heart rate. * Helps control certain **abnormal heart rhythms**. * Reduces the heart's workload and oxygen demand. * Helps prevent or reduce symptoms of **angina (chest pain)**. * May be used after a heart attack in appropriate patients. * Can help control certain symptoms associated with increased sympathetic activity. ## USES / INDICATIONS Metoprolol Tartrate may be prescribed for: * **Hypertension (high blood pressure)**. * **Angina pectoris**. * Certain **tachyarrhythmias (fast heart rhythms)**. * Heart-rate control in selected patients with atrial fibrillation or atrial flutter. * Treatment following **myocardial infarction (heart attack)** in appropriate patients. * Other cardiovascular conditions when specifically prescribed by a healthcare professional. The approved uses can vary by country and product labeling. ## HOW IT WORKS Metoprolol is a **selective beta-1 adrenergic receptor blocker** at usual therapeutic doses. Normally, adrenaline and related hormones stimulate beta-1 receptors in the heart, increasing: * Heart rate. * Force of contraction. * Conduction through the heart. Metoprolol blocks much of this stimulation. ### Overall Action **Metoprolol → blocks beta-1 receptors → slows heart rate + reduces cardiac contractility → decreases cardiac workload and oxygen demand → lowers blood pressure and helps control heart rhythm.** At higher concentrations, beta-1 selectivity may become less pronounced. ## DOSAGE & ADMINISTRATION The appropriate dose depends on: * The condition being treated. * Heart rate and blood pressure. * Age. * Kidney and liver function. * Other medicines. * Individual response to treatment. ### General Administration * Take exactly as prescribed. * Metoprolol tartrate is commonly taken **in divided doses**, depending on the condition. * Take doses at approximately the same time each day. * It may generally be taken with or immediately after food; taking it consistently in relation to meals may help maintain predictable absorption. * Swallow tablets with water. * Do not change the dose without medical advice. ### Metoprolol Tartrate 100 mg A **100 mg tablet** may be prescribed as part of an individualized regimen. The appropriate total daily dose varies considerably depending on the indication. **Do not assume that one 100 mg tablet is an appropriate dose for every patient.** ### Missed Dose Take the missed dose when remembered unless it is nearly time for the next dose. **Do not take two doses together** to compensate for a missed dose. ### Do Not Stop Suddenly Do not abruptly discontinue metoprolol, particularly if it is being used for angina or cardiovascular disease. Sudden withdrawal may cause a rapid increase in heart rate and blood pressure and can worsen angina or increase the risk of serious cardiac complications. Your healthcare professional will generally reduce the dose gradually when discontinuation is necessary. ## SIDE EFFECTS Common side effects may include: * Tiredness or fatigue. * Dizziness. * Slow heartbeat. * Low blood pressure. * Cold hands and feet. * Headache. * Nausea. * Diarrhea or constipation. * Shortness of breath during exertion. * Sleep disturbances or vivid dreams. ### Serious Side Effects Seek medical attention for: * Very slow heartbeat. * Fainting. * Severe dizziness. * New or worsening shortness of breath. * Swelling of the legs or ankles. * Chest pain. * Severe allergic reaction. * Wheezing or difficulty breathing. ## PRECAUTIONS & WARNINGS ### Slow Heart Rate Metoprolol can cause **bradycardia (slow heart rate)**. Your healthcare professional may monitor your pulse and blood pressure during treatment. ### Low Blood Pressure Dizziness or fainting can occur if blood pressure becomes too low. Rise slowly from sitting or lying positions. ### Asthma and Breathing Disorders Although metoprolol is relatively beta-1 selective, it can affect beta-2 receptors at higher doses and may cause **bronchospasm** in susceptible individuals. Tell your healthcare professional if you have: * Asthma. * COPD. * A history of bronchospasm. ### Diabetes Beta-blockers can **mask some warning signs of low blood sugar**, particularly a rapid heartbeat. People with diabetes should monitor blood glucose carefully and discuss symptoms of hypoglycemia with their healthcare professional. ### Heart Failure Metoprolol can be beneficial in selected heart-failure patients, but the **immediate-release tartrate formulation and dosing strategy differ from extended-release formulations used for certain heart-failure indications**. Do not substitute formulations without medical advice. ### Peripheral Circulation Problems Beta-blockers may worsen symptoms of severe peripheral arterial circulation problems in some patients. ### Thyroid Disease Metoprolol can mask some symptoms of hyperthyroidism, particularly a rapid heartbeat. Do not stop treatment suddenly if you have thyroid disease. ### Surgery Tell your surgeon or anesthetist that you are taking metoprolol before undergoing surgery. ### Pregnancy and Breastfeeding Tell your healthcare professional if you are pregnant, planning pregnancy, or breastfeeding. Treatment should be assessed according to the individual clinical situation. ## DRUG INTERACTIONS ### Calcium-Channel Blockers Medicines such as **verapamil and diltiazem** can further slow heart rate and cardiac conduction when combined with metoprolol and may increase the risk of low blood pressure or heart block. ### Other Blood-Pressure Medicines Combining metoprolol with other antihypertensive medicines can produce an additive reduction in blood pressure. ### Digoxin Digoxin and metoprolol can both slow heart rate and AV conduction, increasing the risk of **bradycardia**. ### Antiarrhythmic Medicines Some antiarrhythmics can increase the effects of metoprolol on heart rate and conduction. ### CYP2D6 Inhibitors Medicines such as **fluoxetine, paroxetine, and certain other CYP2D6 inhibitors** can increase metoprolol concentrations and may increase beta-blocker effects. ### Insulin and Antidiabetic Medicines Metoprolol may mask some symptoms of hypoglycemia, especially tachycardia. ### Clonidine Stopping clonidine while taking a beta-blocker can cause a significant rise in blood pressure. If both medicines are being discontinued, the order and timing should be managed by a healthcare professional. ### Other Medicines That Lower Heart Rate Combining metoprolol with other medicines that slow the heart may increase the risk of excessive bradycardia. Always tell your doctor or pharmacist about **all prescription medicines, OTC medicines, vitamins, and herbal supplements** you take. ## STORAGE INFORMATION * Store according to the manufacturer's instructions. * Keep at room temperature unless otherwise specified. * Protect from excessive heat and moisture. * Keep away from direct sunlight. * Keep tablets in their original packaging. * Keep out of reach of children. * Do not use after the expiry date. * Do not use tablets from damaged or tampered packaging. ## PRESCRIPTION STATUS **Metoprolol Tartrate 100 mg is a prescription medicine.** It should be used under medical supervision because it can significantly affect heart rate and blood pressure and may interact with several cardiovascular medicines. Prescription requirements may vary by country. ## GENUINE MEDICINE ASSURANCE When purchasing **Metoprolol Tartrate 100 mg**, obtain it from a **licensed pharmacy or authorized medicine supplier**. Check: * Active ingredient: **Metoprolol Tartrate**. * Strength: **100 mg**. * Formulation: immediate-release metoprolol tartrate. * Manufacturer details. * Batch/lot number. * Manufacturing date. * Expiry date. * Intact packaging and seal. * Clear labeling and dosage instructions. Avoid products with damaged packaging, missing batch information, unclear labeling, or questionable authenticity. > **Important:** Metoprolol tartrate and metoprolol succinate are different formulations and should **not be substituted without medical advice**. ## FREQUENTLY ASKED QUESTIONS (FAQ) ### 1. What is Metoprolol Tartrate 100 mg used for? Metoprolol Tartrate 100 mg is used to treat conditions such as **high blood pressure, angina, certain fast heart rhythms, and selected patients after a heart attack**. ### 2. Is metoprolol a beta-blocker? Yes. Metoprolol is a **beta-blocker that primarily blocks beta-1 receptors in the heart**. ### 3. Does metoprolol lower blood pressure? Yes. It lowers blood pressure partly by reducing heart rate and the force of cardiac contraction and by reducing sympathetic nervous-system activity. ### 4. Does metoprolol lower heart rate? Yes. One of its main effects is to **slow the heart rate**. ### 5. What is the difference between metoprolol tartrate and metoprolol succinate? **Metoprolol tartrate** is an immediate-release formulation commonly administered more than once daily depending on the indication. **Metoprolol succinate extended-release** is a modified-release formulation designed for once-daily administration for specific indications. They should not be substituted without professional guidance. ### 6. Is Metoprolol Tartrate 100 mg a high dose? 100 mg is a significant tablet strength, but whether it is a high or appropriate dose depends on the condition being treated, total daily dose, and individual response. ### 7. Can I take metoprolol with food? Metoprolol tartrate is commonly taken with or immediately after meals. Follow the instructions supplied with your particular product and take it consistently in relation to food. ### 8. What happens if I miss a dose of metoprolol? Take it when remembered unless it is nearly time for the next dose. **Do not double the next dose.** ### 9. Can I stop metoprolol suddenly? **No.** Abrupt withdrawal can cause rapid increases in heart rate and blood pressure and may worsen angina or increase cardiovascular risk. ### 10. Does metoprolol cause tiredness? Yes. **Fatigue or tiredness** is a common side effect, particularly when treatment is first started. ### 11. Does metoprolol cause dizziness? Yes. Dizziness may occur due to reduced blood pressure or heart rate. ### 12. Can metoprolol cause a slow heartbeat? Yes. **Bradycardia** is a recognized effect of metoprolol. Contact your healthcare professional if you experience fainting, severe weakness, or symptoms associated with an unusually slow heartbeat. ### 13. Can people with asthma take metoprolol? Metoprolol is relatively beta-1 selective, but it can still cause bronchospasm, especially at higher doses. People with asthma should use it only after discussing the risks with their healthcare professional. ### 14. Can metoprolol be taken with diabetes medicines? It can be used in people with diabetes, but beta-blockers may **mask some symptoms of low blood sugar**, especially a rapid heartbeat. Blood glucose should be monitored appropriately. ### 15. Can metoprolol be taken with amlodipine? Metoprolol and amlodipine can sometimes be used together for blood-pressure or cardiovascular treatment. Medical monitoring may be required because both can lower blood pressure. ### 16. Can metoprolol be taken with diltiazem? The combination can significantly slow heart rate and cardiac conduction. It should only be used together when specifically prescribed and monitored by a healthcare professional. ### 17. Can metoprolol be taken with alcohol? Alcohol may increase dizziness or low blood pressure in some people. Discuss alcohol consumption with your healthcare professional. ### 18. Does metoprolol cause weight gain? Some people may experience weight changes during beta-blocker treatment, although significant weight gain is not inevitable. Diet, activity, and the underlying condition can also affect weight. ### 19. Can metoprolol be used during pregnancy? Metoprolol may sometimes be used during pregnancy when clinically necessary, but treatment should be individually assessed by a healthcare professional. ### 20. Can metoprolol be used while breastfeeding? Metoprolol passes into breast milk in small amounts. Discuss breastfeeding with your healthcare professional to determine whether it is appropriate for you. ### 21. Does metoprolol treat anxiety? Although beta-blockers can reduce some physical symptoms associated with adrenaline, metoprolol is primarily prescribed for **cardiovascular conditions** and should not be self-used to treat anxiety. ### 22. Can metoprolol treat irregular heartbeat? Yes. Metoprolol can be used to **control heart rate in certain arrhythmias**, including selected patients with atrial fibrillation or atrial flutter. ### 23. Can metoprolol protect the heart after a heart attack? Metoprolol may be prescribed after a heart attack in appropriate patients to reduce cardiac workload and certain cardiovascular risks. ### 24. Is Metoprolol Tartrate 100 mg prescription-only? Yes. Metoprolol is generally a **prescription medicine** and should be taken under appropriate medical supervision. ### 25. How should Metoprolol Tartrate 100 mg be stored? Store according to the manufacturer's instructions, generally at room temperature and protected from **heat, moisture, and direct sunlight**. Keep out of reach of children. ## MEDICAL DISCLAIMER This information about **Metoprolol Tartrate 100 mg** is provided for general educational and informational purposes only. It does not replace professional medical advice, diagnosis, or treatment. Metoprolol is a prescription beta-blocker that can significantly affect **heart rate and blood pressure**. The appropriate dose depends on the condition being treated, other medicines, cardiovascular status, and individual response. **Do not stop metoprolol suddenly** without medical guidance, particularly if you have coronary artery disease or angina. Seek urgent medical attention for severe chest pain, fainting, severe breathing difficulty, or symptoms of a dangerously slow heartbeat. Always consult a qualified healthcare professional before starting, stopping, or changing the dose of Metoprolol Tartrate 100 mg.