TELCLOR 12.5 80

# Chlorthalidone 12.5 mg + Telmisartan 80 mg ## SHORT DESCRIPTION Chlorthalidone 12.5 mg + Telmisartan 80 mg is a combination medicine used to help control **high blood pressure (hypertension)**. It combines telmisartan, an angiotensin II receptor blocker (ARB), with chlorthalidone, a thiazide-like diuretic. Together, they lower blood pressure through complementary mechanisms and may help reduce the risk of complications associated with uncontrolled hypertension. ## KEY BENEFITS * Helps lower and control high blood pressure * Combines two complementary blood pressure-lowering mechanisms * Helps reduce excess sodium and fluid in the body * May reduce the risk of cardiovascular complications associated with uncontrolled hypertension * Convenient combination therapy when both medicines are clinically appropriate * May help achieve blood pressure targets when a single medicine is insufficient ## USES / INDICATIONS Chlorthalidone 12.5 mg + Telmisartan 80 mg may be prescribed for: * Hypertension (high blood pressure) * Blood pressure control when combination therapy is required * Patients who require an ARB together with a diuretic for adequate blood pressure control This medicine is generally used alongside lifestyle measures such as a balanced diet, appropriate physical activity, and reduced sodium intake. ## HOW IT WORKS **Telmisartan:** Telmisartan blocks the action of angiotensin II at AT1 receptors. Angiotensin II normally causes blood vessels to constrict and promotes sodium and water retention. Blocking its action relaxes blood vessels and reduces blood pressure. **Chlorthalidone:** Chlorthalidone is a thiazide-like diuretic. It increases the elimination of sodium and water through the kidneys, reducing fluid volume and contributing to lower blood pressure. Together, these medicines provide complementary blood pressure-lowering effects. ## DOSAGE & ADMINISTRATION * Take this medicine exactly as prescribed by your doctor. * It is generally taken **once daily**, with or without food. * Take it at approximately the same time each day. * Swallow the tablet with water; do not crush or chew it unless specifically instructed. * Because chlorthalidone increases urination, taking the medicine earlier in the day may be preferable for some patients. * Do not change the dose or stop treatment without consulting your doctor. * Your doctor may regularly monitor blood pressure, kidney function, and electrolyte levels such as potassium and sodium. ## SIDE EFFECTS Possible side effects may include: * Dizziness * Headache * Increased urination * Weakness or fatigue * Low blood pressure * Nausea * Changes in blood potassium or sodium levels * Increased uric acid levels * Increased blood glucose levels Seek medical attention if you experience severe dizziness, fainting, significant muscle weakness, irregular heartbeat, swelling of the face or throat, or other serious symptoms. ## PRECAUTIONS & WARNINGS * Inform your doctor if you have kidney or liver disease. * Tell your healthcare professional if you have diabetes, gout, high uric acid levels, or electrolyte abnormalities. * Regular monitoring of kidney function and electrolytes may be required. * Chlorthalidone may increase uric acid levels and may trigger gout in susceptible individuals. * Excessive fluid loss may cause dehydration or low blood pressure, particularly in hot weather or during vomiting or diarrhoea. * Rise slowly from sitting or lying positions if you experience dizziness. * Avoid potassium supplements or potassium-containing salt substitutes unless recommended by your doctor. * **Telmisartan should not be used during pregnancy.** Contact your doctor immediately if pregnancy occurs while taking this medicine. * Inform your doctor if you are breastfeeding. * Do not discontinue antihypertensive treatment without medical advice. ## DRUG INTERACTIONS This combination may interact with: * Potassium supplements and potassium-containing salt substitutes * Other medicines that increase potassium levels * ACE inhibitors * Other angiotensin receptor blockers * Aliskiren * NSAIDs such as ibuprofen, diclofenac, or naproxen * Lithium * Digoxin * Other diuretics or blood-pressure-lowering medicines * Medicines that can affect blood glucose or uric acid levels NSAIDs may reduce the blood-pressure-lowering effect and can increase the risk of kidney problems when combined with medicines affecting the renin-angiotensin system and diuretics. Always inform your doctor or pharmacist about all prescription medicines, over-the-counter medicines, vitamins, and supplements you take. ## STORAGE INFORMATION * Store at room temperature according to the manufacturer's instructions. * Keep away from excessive heat, moisture, and direct sunlight. * Keep the medicine in its original packaging. * Keep out of reach and sight of children. * Do not use after the expiry date printed on the package. * Keep the packaging tightly closed when not in use. ## PRESCRIPTION STATUS Chlorthalidone 12.5 mg + Telmisartan 80 mg is generally a **prescription medicine**. It should be used under the supervision of a qualified healthcare professional, particularly because blood pressure, kidney function, and electrolyte levels may require monitoring. ## GENUINE MEDICINE ASSURANCE For genuine medicine assurance: * Purchase the medicine from a licensed and reputable pharmacy. * Check the product name, strength, batch number, manufacturer details, and expiry date. * Ensure the packaging and seal are intact. * Do not use products with damaged, altered, or suspicious packaging. * Store the medicine according to the manufacturer's instructions. * Consult a pharmacist if you have concerns about product authenticity. ## FAQ ### What is Chlorthalidone 12.5 mg + Telmisartan 80 mg used for? It is used to treat high blood pressure. The combination provides two different mechanisms for lowering blood pressure and may be prescribed when combination treatment is appropriate. ### Is Telmisartan a blood pressure medicine? Yes. Telmisartan is an angiotensin II receptor blocker (ARB) used to lower blood pressure and, in appropriate patients, help reduce cardiovascular risk. ### What is Chlorthalidone used for? Chlorthalidone is a diuretic that helps the kidneys remove excess sodium and water. It is commonly used to treat high blood pressure and fluid retention in certain conditions. ### Can Chlorthalidone and Telmisartan be taken together? Yes. They are specifically combined in some treatment regimens because they lower blood pressure through complementary mechanisms. The combination should be taken only as prescribed. ### When should I take Chlorthalidone + Telmisartan? It is generally taken once daily. Because chlorthalidone can increase urination, taking it earlier in the day may help reduce nighttime urination. Follow your doctor's instructions. ### Can I take this medicine with food? Yes. The combination can generally be taken with or without food. Taking it consistently at the same time each day is recommended. ### Does this medicine cause frequent urination? Chlorthalidone increases the amount of sodium and water eliminated by the kidneys, so increased urination can occur, particularly after starting treatment. ### Can Chlorthalidone + Telmisartan lower potassium? Chlorthalidone can lower potassium levels, while telmisartan can increase potassium levels. The overall effect varies between individuals, so your doctor may monitor potassium and other electrolytes. ### Can this medicine affect kidney function? Yes. Telmisartan and chlorthalidone can affect kidney function, particularly in people who are dehydrated or already have kidney disease. Your doctor may monitor kidney function through blood tests. ### Can I take ibuprofen with Telmisartan and Chlorthalidone? NSAIDs such as ibuprofen can reduce the blood-pressure-lowering effect and may increase the risk of kidney problems when used with an ARB and diuretic. Consult your doctor or pharmacist before regular use. ### Can I take this medicine during pregnancy? No. Telmisartan can cause serious harm to an unborn baby and should not be used during pregnancy. If you become pregnant while taking this medicine, contact your doctor promptly. ### Can this medicine cause dizziness? Yes. Blood pressure may become too low, particularly when treatment is started or the dose is changed. If you experience dizziness, rise slowly and inform your doctor if symptoms are severe or persistent. ### What should I do if I miss a dose? Take the missed dose when you remember unless it is nearly time for the next dose. Do not take two doses together to make up for a missed dose. ### Can I stop this medicine when my blood pressure becomes normal? Do not stop treatment without medical advice. Normal blood pressure may indicate that the medicine is controlling your condition rather than that hypertension has been cured. ### Do I need to follow a special diet while taking this medicine? A heart-healthy, lower-sodium diet and regular physical activity are commonly recommended for people with hypertension. Avoid potassium supplements or potassium-containing salt substitutes unless your healthcare professional recommends them. ## MEDICAL DISCLAIMER This information is provided for educational and informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Chlorthalidone 12.5 mg + Telmisartan 80 mg should be used only as directed by a qualified healthcare professional. The appropriate treatment may vary according to blood pressure, kidney function, electrolyte levels, age, medical conditions, and other medicines being used. Telmisartan should not be used during pregnancy. Always read the product label and consult your doctor or pharmacist for personalized guidance.