TELCLOR 6.25/40

# Chlorthalidone 6.25 mg + Telmisartan 40 mg ## Short Description Chlorthalidone 6.25 mg + Telmisartan 40 mg is a **prescription combination medicine used to lower high blood pressure (hypertension)**. It combines telmisartan, an angiotensin II receptor blocker (ARB), with chlorthalidone, a thiazide-like diuretic. Together, they help reduce blood pressure through complementary mechanisms. ## Key Benefits * Helps lower high blood pressure * Combines two complementary blood-pressure-lowering medicines * Telmisartan helps relax blood vessels * Chlorthalidone helps remove excess sodium and water * May help reduce the long-term risk of complications associated with uncontrolled hypertension * Can be useful when blood pressure is not adequately controlled with a single medicine ## Uses / Indications Chlorthalidone 6.25 mg + Telmisartan 40 mg may be prescribed for: * **Hypertension (high blood pressure)** * Blood pressure that remains elevated despite treatment with one medicine * Patients who require combination antihypertensive therapy * Reduction of cardiovascular risk through effective blood-pressure control, when clinically appropriate It is not intended to provide immediate treatment for a hypertensive emergency. ## How It Works **Telmisartan** blocks the action of angiotensin II at AT1 receptors. Angiotensin II normally causes blood vessels to narrow and promotes sodium retention. Blocking its effects helps **relax blood vessels and lower blood pressure**. **Chlorthalidone** is a thiazide-like diuretic. It increases the excretion of sodium and water through the kidneys, reducing fluid volume and contributing to lower blood pressure. The two medicines work together to provide more effective blood-pressure control in appropriate patients. ## Dosage & Administration * Take Chlorthalidone 6.25 mg + Telmisartan 40 mg exactly as prescribed * It is usually taken **once daily**, but follow your doctor's specific instructions * Take it at approximately the same time each day * It may be taken with or without food * Swallow the tablet whole with water * Because chlorthalidone increases urination, taking the medicine in the morning may be preferable * Do not change the dose without medical advice * Continue taking it even if you feel well, because hypertension often has no noticeable symptoms * If you miss a dose, take it when remembered unless it is close to the next dose * Do not take two doses together to compensate for a missed dose * Your doctor may monitor blood pressure, kidney function and electrolytes during treatment ## Side Effects Common side effects may include: * Dizziness * Headache * Increased urination * Fatigue * Low blood pressure * Nausea * Changes in blood electrolyte levels Chlorthalidone may cause: * Low potassium * Low sodium * Increased uric acid * Increased blood glucose * Dehydration Telmisartan may cause: * Dizziness * Increased potassium levels * Changes in kidney function Seek urgent medical attention for severe dizziness or fainting, facial or throat swelling, difficulty breathing, severe weakness or significant changes in urination. ## Precautions & Warnings * Monitor blood pressure regularly, particularly when starting treatment or changing the dose * Tell your doctor if you have **kidney disease or liver disease** * Your doctor may monitor potassium, sodium, creatinine and other blood tests * Chlorthalidone can cause dehydration and electrolyte abnormalities * Tell your doctor if you have gout or high uric acid because chlorthalidone may increase uric acid levels * Tell your doctor if you have diabetes because chlorthalidone can affect blood glucose * Avoid excessive alcohol because it may increase dizziness and low blood pressure * Rise slowly from sitting or lying positions to reduce dizziness * **Do not use telmisartan during pregnancy**; medicines affecting the renin-angiotensin system can cause serious fetal harm * Tell your doctor if you become pregnant while taking this medicine * Do not use potassium supplements or potassium-containing salt substitutes unless recommended by your doctor * Keep out of reach of children ## Drug Interactions Tell your doctor or pharmacist about all prescription medicines, OTC medicines, supplements and herbal products you use. Important interactions include: * **ACE inhibitors** — combining with telmisartan can increase the risk of low blood pressure, kidney problems and high potassium * **Aliskiren** — particularly important in people with diabetes or kidney impairment * **Potassium supplements and potassium-containing salt substitutes** — may increase potassium levels * **Potassium-sparing diuretics** such as spironolactone — may increase potassium * **NSAIDs** such as ibuprofen or naproxen — may reduce blood-pressure control and increase kidney risk * **Lithium** — diuretics and ARBs can increase lithium levels and toxicity risk * Other blood-pressure medicines — may cause excessive blood-pressure reduction * **Digoxin and other medicines affected by electrolyte changes** may require monitoring * **Antidiabetic medicines** may require adjustment because chlorthalidone can affect blood glucose Avoid starting supplements or medicines without informing your healthcare professional. ## Storage Information * Store according to the manufacturer's instructions * Keep tablets in their original packaging * Protect from excessive heat, moisture and direct sunlight * Keep the container tightly closed * Keep out of reach and sight of children * Do not use after the expiry date * Follow the specific storage instructions printed on the product label ## Prescription Status Chlorthalidone 6.25 mg + Telmisartan 40 mg is generally a **prescription-only medicine**. It should be used under the supervision of a qualified healthcare professional. ## Genuine Medicine Assurance * Purchase the medicine only from a licensed and reputable pharmacy * Use it only against a valid prescription * Check the medicine name and **6.25 mg/40 mg strengths** * Verify the batch number and expiry date * Ensure the packaging and seal are intact * Do not use tablets from damaged, altered or suspicious packaging * Confirm that the strength matches your prescription * Purchase medicines from authorized sources * If you suspect the medicine is counterfeit, consult a pharmacist or the appropriate medicine regulatory authority ## Frequently Asked Questions ### What is Chlorthalidone 6.25 mg + Telmisartan 40 mg used for? It is a combination medicine used primarily to **treat high blood pressure (hypertension)** when combination therapy is appropriate. ### Is Telmisartan a blood pressure medicine? Yes. Telmisartan is an **angiotensin II receptor blocker (ARB)** used to lower blood pressure. ### What is Chlorthalidone used for? Chlorthalidone is a thiazide-like diuretic that helps the kidneys remove sodium and water. It is commonly used to lower blood pressure. ### Why are Chlorthalidone and Telmisartan combined? They lower blood pressure through different mechanisms. Telmisartan relaxes blood vessels, while chlorthalidone reduces sodium and fluid volume. ### How should I take Telmisartan 40 mg + Chlorthalidone 6.25 mg? Take it exactly as prescribed, usually once daily. It can generally be taken with or without food. ### Should I take this medicine in the morning? Because chlorthalidone can increase urination, taking the combination in the morning may be more convenient. Follow your doctor's instructions if a different schedule has been prescribed. ### Can this medicine cure high blood pressure? It helps **control high blood pressure**, but hypertension usually requires long-term management rather than a short course of treatment. ### Can I stop taking Telmisartan and Chlorthalidone when my blood pressure improves? Do not stop the medicine without consulting your doctor. Blood pressure can rise again after treatment is stopped. ### Does Chlorthalidone cause frequent urination? Yes. Increased urination is expected because chlorthalidone promotes the removal of excess sodium and water through the kidneys. ### Can this medicine cause dizziness? Yes. Dizziness or lightheadedness can occur, particularly when treatment is started or blood pressure becomes too low. ### Can Chlorthalidone lower potassium? Yes. Chlorthalidone can lower potassium levels. Your doctor may monitor electrolytes during treatment. ### Can Telmisartan increase potassium? Yes. Telmisartan can increase blood potassium in some patients. This is one reason potassium levels may need monitoring. ### Can I take potassium supplements with Telmisartan? Do not take potassium supplements or potassium-containing salt substitutes unless your doctor specifically recommends them. ### Can I take Ibuprofen with Telmisartan and Chlorthalidone? NSAIDs such as ibuprofen can reduce the blood-pressure-lowering effect and may increase the risk of kidney problems, particularly in people who are dehydrated or have kidney disease. Consult your doctor before using them regularly. ### Can this medicine be used during pregnancy? **Telmisartan should not be used during pregnancy.** If you become pregnant while taking this medicine, contact your doctor promptly. ### Can I drink alcohol while taking this medicine? Alcohol may increase dizziness and low blood pressure. It is advisable to limit or avoid alcohol and follow your healthcare professional's advice. ### Does Chlorthalidone affect blood sugar? Yes. Chlorthalidone can sometimes increase blood glucose levels. People with diabetes may require additional monitoring. ### Can Chlorthalidone affect uric acid? Yes. Chlorthalidone can increase uric acid levels and may worsen gout in susceptible individuals. ### Does this medicine affect the kidneys? Telmisartan and chlorthalidone can affect kidney function in certain patients. Your doctor may monitor kidney function, especially if you have existing kidney disease or take medicines that affect the kidneys. ### What happens if I miss a dose? Take the missed dose when you remember unless it is close to the next scheduled dose. Do not take a double dose. ### How long does Telmisartan take to work? Telmisartan begins lowering blood pressure after treatment starts, but the full blood-pressure-lowering effect may take several weeks with continued treatment. ### Is Chlorthalidone a strong diuretic? Chlorthalidone is a relatively long-acting thiazide-like diuretic. Its appropriate dose depends on the patient's condition and response. ### Can I take other blood pressure medicines with this combination? Additional blood-pressure medicines may sometimes be prescribed, but combining treatments can lower blood pressure excessively or affect kidney function and electrolytes. Use additional medicines only as directed by your doctor. ### How often should my blood pressure be checked? Your healthcare professional will determine an appropriate monitoring schedule. Regular home blood-pressure monitoring can be useful for assessing treatment response. ## Medical Disclaimer This information is provided for general educational purposes only and is not a substitute for professional medical advice, diagnosis or treatment. Chlorthalidone 6.25 mg + Telmisartan 40 mg is a prescription medicine and should be used only under the supervision of a qualified healthcare professional. The appropriate dose depends on blood pressure, kidney and liver function, electrolyte levels, other medicines and individual patient factors. **Telmisartan must not be used during pregnancy.** Do not change or stop treatment without medical advice. Seek urgent medical attention for severe allergic reactions, fainting, severe weakness, significant changes in urination or other serious symptoms.