TGR 160MG

# Fenofibrate 160 mg ## SHORT DESCRIPTION Fenofibrate 160 mg is a lipid-lowering medicine belonging to the **fibrate** class. It is used to help manage abnormal levels of fats in the blood, particularly high triglycerides and certain types of high cholesterol. It is generally used along with a healthy diet, regular physical activity, and other lifestyle measures. Fenofibrate should be taken according to a healthcare professional's advice. ## KEY BENEFITS * Helps reduce elevated triglyceride levels * Helps lower certain types of cholesterol, including LDL cholesterol * May increase beneficial HDL cholesterol levels * Helps improve an abnormal blood lipid profile * Supports management of mixed dyslipidaemia when appropriate * Can be used as part of a comprehensive cholesterol-management plan ## USES / INDICATIONS Fenofibrate 160 mg may be prescribed for: * Hypertriglyceridaemia * Mixed dyslipidaemia * Elevated cholesterol and triglyceride levels * Certain lipid disorders that require fibrate therapy * Severe hypertriglyceridaemia, when clinically appropriate Fenofibrate is usually prescribed together with dietary and lifestyle changes. ## HOW IT WORKS Fenofibrate activates **peroxisome proliferator-activated receptor alpha (PPAR-α)**. This increases the breakdown and clearance of triglyceride-rich particles from the bloodstream and can reduce the production of certain lipoproteins. As a result, triglyceride levels generally decrease, while HDL cholesterol may increase. ## DOSAGE & ADMINISTRATION * Take Fenofibrate 160 mg exactly as prescribed by your doctor. * The usual adult dose depends on the specific formulation and the patient's lipid levels and kidney function. * Some fenofibrate formulations are taken **once daily with food**, while certain formulations may have different administration instructions. * Swallow the tablet whole with water unless your product specifically allows otherwise. * Follow the instructions provided with your particular brand because different fenofibrate formulations are not always interchangeable on a milligram-for-milligram basis. * Continue dietary and lifestyle measures recommended by your healthcare professional. * Your doctor may monitor cholesterol and triglyceride levels and may adjust treatment accordingly. * Patients with reduced kidney function may require a lower dose or a different treatment approach. ## SIDE EFFECTS Possible side effects may include: * Nausea * Abdominal discomfort * Diarrhoea * Headache * Increased liver enzymes * Muscle pain or weakness * Changes in kidney function * Skin rash Rarely, fenofibrate may cause serious muscle injury, gallbladder problems, liver injury, or severe allergic reactions. Seek immediate medical attention for severe unexplained muscle pain or weakness, dark urine, yellowing of the skin or eyes, severe abdominal pain, or signs of a serious allergic reaction. ## PRECAUTIONS & WARNINGS * Inform your doctor if you have kidney or liver disease. * Tell your healthcare professional if you have a history of gallbladder disease. * Fenofibrate may increase the risk of muscle-related adverse effects, particularly when combined with certain statins. * Report unexplained muscle pain, tenderness, or weakness promptly. * Your doctor may periodically monitor liver function, kidney function, and lipid levels. * Fenofibrate is not suitable for everyone with high cholesterol; treatment depends on the type and cause of the lipid abnormality. * Use during pregnancy or breastfeeding only when specifically recommended by a healthcare professional. * Inform your doctor about all medicines and supplements you are taking. * Continue a heart-healthy diet and exercise program as recommended. ## DRUG INTERACTIONS Fenofibrate may interact with: * Statins such as atorvastatin, rosuvastatin, or simvastatin * Warfarin and other anticoagulants * Certain medicines that affect kidney function * Other lipid-lowering medicines * Some medicines that may increase the risk of gallstones or muscle-related adverse effects Combining fenofibrate with a statin can increase the risk of muscle injury in some patients. If you take warfarin, your doctor may need to monitor blood clotting more closely. Always inform your doctor or pharmacist about prescription medicines, over-the-counter medicines, vitamins, and supplements you use. ## STORAGE INFORMATION * Store at room temperature as directed on the product packaging. * Keep away from excessive heat, moisture, and direct sunlight. * Keep the medicine in its original packaging. * Keep out of reach and sight of children. * Do not use after the expiry date printed on the package. ## PRESCRIPTION STATUS Fenofibrate 160 mg is generally a **prescription medicine**. It should be used under the supervision of a qualified healthcare professional, particularly because treatment may require monitoring of lipid levels, kidney function, and liver function. ## GENUINE MEDICINE ASSURANCE For genuine medicine assurance: * Purchase Fenofibrate 160 mg from a licensed and reputable pharmacy. * Check the medicine name, strength, batch number, manufacturer information, and expiry date. * Ensure the packaging and seal are intact. * Do not use products with damaged, altered, or suspicious packaging. * Follow the manufacturer's storage instructions. * Consult a pharmacist if you have concerns about the authenticity of the medicine. ## FAQ ### What is Fenofibrate 160 mg used for? Fenofibrate 160 mg is used to help manage high triglycerides, mixed dyslipidaemia, and certain types of abnormal cholesterol levels. It is usually used alongside diet and lifestyle changes. ### Does Fenofibrate lower triglycerides? Yes. Fenofibrate is particularly effective at reducing elevated triglyceride levels and may also improve other components of an abnormal lipid profile. ### Does Fenofibrate lower cholesterol? Yes. Fenofibrate can reduce certain cholesterol levels, including LDL cholesterol in some patients, while generally increasing HDL cholesterol. The effect varies depending on the individual's lipid profile. ### Is Fenofibrate a statin? No. Fenofibrate belongs to the **fibrate** class of lipid-lowering medicines. Statins, such as atorvastatin and rosuvastatin, belong to a different class and primarily reduce LDL cholesterol. ### Can Fenofibrate be taken with a statin? Fenofibrate may sometimes be prescribed with a statin when additional lipid control is needed. However, the combination can increase the risk of muscle-related side effects, so it should only be used under medical supervision. ### When should I take Fenofibrate 160 mg? The timing depends on the specific formulation. Some fenofibrate tablets are taken once daily with food. Always follow the instructions provided with your particular product. ### Can Fenofibrate be taken without food? This depends on the formulation. Some fenofibrate products require administration with food, while others can be taken without regard to meals. Check the product-specific instructions or ask your pharmacist. ### Does Fenofibrate help with weight loss? No. Fenofibrate is not a weight-loss medicine. It is prescribed to manage abnormal blood lipid levels. ### How long does Fenofibrate take to work? Changes in triglyceride and cholesterol levels may become noticeable over several weeks. Your doctor may perform follow-up blood tests to determine how well the treatment is working. ### Can Fenofibrate cause muscle pain? Yes. Muscle pain or weakness can occur. The risk may be higher when fenofibrate is combined with certain statins. Report unexplained or severe muscle symptoms to your doctor promptly. ### Can Fenofibrate affect the liver? Fenofibrate can increase liver enzymes in some people and, rarely, may cause significant liver injury. Your doctor may recommend liver-function monitoring during treatment. ### Can Fenofibrate affect the kidneys? Fenofibrate can cause changes in kidney function, and dose adjustment may be necessary in people with reduced kidney function. Your doctor may monitor kidney function during treatment. ### What should I do if I miss a dose? Take the missed dose when you remember unless it is nearly time for your next dose. Do not take two doses together to make up for a missed dose. Follow your doctor's specific instructions. ### Is Fenofibrate safe during pregnancy? Fenofibrate is generally not routinely used during pregnancy unless a healthcare professional determines that treatment is necessary. Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding. ## MEDICAL DISCLAIMER This information is provided for educational and informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Fenofibrate 160 mg should be used only as directed by a qualified healthcare professional. The appropriate dose and formulation may vary according to lipid levels, kidney function, liver function, age, and other medical conditions. Do not start, stop, or change the dose without medical advice. Always read the product label and consult your doctor or pharmacist for personalized guidance.