TRICAINE MPS

# ALUMINIUM HYDROXIDE 300 MG + MAGNESIUM HYDROXIDE 150 MG + OXETHAZAINE 10 MG + SIMETHICONE 125 MG ## SHORT DESCRIPTION This combination medicine contains **Aluminium Hydroxide 300 mg, Magnesium Hydroxide 150 mg, Oxethazaine 10 mg, and Simethicone 125 mg**. It is an **antacid and gastrointestinal symptom-relief medicine** used for conditions associated with excess stomach acid, gas, bloating, and painful acid-related gastrointestinal symptoms. * **Aluminium hydroxide + Magnesium hydroxide:** Neutralize excess stomach acid. * **Oxethazaine:** A local anesthetic that helps temporarily relieve pain or burning in the stomach and upper gastrointestinal tract. * **Simethicone:** Helps break up gas bubbles, reducing bloating and abdominal discomfort. --- ## KEY BENEFITS * Provides **rapid symptomatic relief from excess stomach acidity**. * Helps relieve **heartburn and acid indigestion**. * Can reduce **gas-related bloating and abdominal discomfort**. * Oxethazaine provides local relief from **painful burning or irritation** associated with acid-related conditions. * The combination provides multiple mechanisms for relieving **acidity, gas, and gastrointestinal discomfort**. * May be used for symptomatic relief in conditions such as gastritis or acid-related dyspepsia, when recommended by a healthcare professional. > **Important:** This medicine provides symptomatic relief and may not treat the underlying cause of persistent stomach pain, ulcers, or gastroesophageal reflux disease (GERD). --- ## USES / INDICATIONS This combination may be used for symptomatic relief of: ### 1. Heartburn and Acid Indigestion The antacid components neutralize excess gastric acid and can relieve: * Heartburn * Acid indigestion * Sour stomach * Acid-related discomfort ### 2. Gastritis-Related Symptoms It may help temporarily relieve burning and discomfort associated with gastritis when recommended by a healthcare professional. ### 3. Acid-Related Dyspepsia The combination can help relieve symptoms such as: * Upper abdominal discomfort * Burning * Acid-related pain * Bloating ### 4. Gas and Bloating Simethicone helps reduce symptoms caused by trapped gas, including: * Abdominal bloating * Fullness * Gas-related discomfort ### 5. Painful Acid-Related Gastrointestinal Symptoms Oxethazaine provides temporary local anesthetic action and may help relieve painful burning associated with acid-related gastrointestinal irritation. --- ## HOW IT WORKS This medicine contains four active ingredients with complementary actions. ### Aluminium Hydroxide 300 mg Aluminium hydroxide is an **antacid**. It reacts with and neutralizes stomach hydrochloric acid, increasing gastric pH and reducing acid-related irritation. ### Magnesium Hydroxide 150 mg Magnesium hydroxide is another antacid that neutralizes gastric acid. It can also have a **laxative effect** at higher doses. The combination of aluminium hydroxide and magnesium hydroxide can help balance their effects on bowel movements, as aluminium may cause constipation while magnesium may loosen stools. ### Oxethazaine 10 mg Oxethazaine is a **local anesthetic**. It temporarily reduces the sensation of pain in the gastrointestinal tract, helping relieve burning and painful irritation. ### Simethicone 125 mg Simethicone is an **antifoaming agent**. It reduces the surface tension of gas bubbles in the gastrointestinal tract, allowing small bubbles to combine and pass more easily. ### Simple Explanation **Antacids → neutralize stomach acid** **Oxethazaine → reduces gastrointestinal pain sensation** **Simethicone → reduces trapped gas and bloating** --- ## DOSAGE & ADMINISTRATION ### Adults The appropriate dose depends on the specific product formulation and the condition being treated. For this combination, **follow the dosage printed on the product label or prescribed by your healthcare professional**. Because the product contains oxethazaine, it should not be used more frequently or for longer than recommended. ### How to Take * Take exactly as directed. * If supplied as a suspension, **shake well before use**. * Measure liquid doses with the supplied measuring device rather than a household spoon. * If tablets are supplied, take them according to the product instructions. * Do not exceed the recommended dose. * Keep an appropriate interval between this medicine and other oral medicines because antacids can interfere with absorption. ### When to Take Depending on the product and indication, it may be taken **after meals and/or at bedtime**. Always follow the specific product instructions or your doctor's recommendation. ### Children Use in children should be based on medical advice. Do not give this combination to children without checking the appropriate dose with a healthcare professional. ### Missed Dose If being used regularly and a dose is missed, take it when remembered unless it is nearly time for the next dose. **Do not double the dose.** --- ## SIDE EFFECTS ### Common Side Effects Possible side effects include: * Constipation * Diarrhea * Nausea * Abdominal discomfort * Changes in bowel movements * Altered taste * Mild stomach upset ### Effects Related to Aluminium Aluminium-containing antacids may cause: * Constipation * Reduced phosphate levels with prolonged excessive use ### Effects Related to Magnesium Magnesium hydroxide may cause: * Loose stools * Diarrhea * Abdominal cramping People with kidney impairment are at greater risk of magnesium accumulation. ### Oxethazaine-Related Effects Possible effects may include: * Numbness of the mouth or throat * Altered sensation * Dizziness * Rare allergic reactions ### Serious Side Effects Seek medical attention for: * Difficulty breathing * Facial or throat swelling * Severe rash * Persistent vomiting * Severe abdominal pain * Significant weakness or confusion --- ## PRECAUTIONS & WARNINGS ### Kidney Disease People with moderate or severe kidney impairment should consult a healthcare professional before using this medicine. Aluminium and magnesium can accumulate when kidney function is significantly reduced. ### Prolonged Use Do not use this combination continuously for an extended period without medical supervision. Long-term excessive antacid use can contribute to: * Electrolyte abnormalities * Altered phosphate levels * Aluminium accumulation * Magnesium accumulation in susceptible individuals ### Persistent Abdominal Pain Do not use this medicine simply to mask unexplained or persistent abdominal pain. Seek medical evaluation for: * Persistent or worsening pain * Repeated vomiting * Unexplained weight loss * Difficulty swallowing * Black/tarry stools * Vomiting blood * Persistent heartburn ### Pregnancy Consult a healthcare professional before using this combination during pregnancy, particularly for prolonged treatment. ### Breastfeeding Consult your healthcare professional before prolonged use while breastfeeding. ### Local Anesthetic Effect Oxethazaine can temporarily reduce sensation in the gastrointestinal tract. Follow the recommended dose and avoid unnecessary prolonged use. ### Sodium Content Check the product formulation if you follow a sodium-restricted diet, as some antacid formulations may contain additional sodium-containing ingredients. --- ## DRUG INTERACTIONS Antacids can interfere with the absorption of many oral medicines. ### Antibiotics Aluminium and magnesium can reduce absorption of certain antibiotics, including: * Tetracyclines such as doxycycline * Fluoroquinolones such as ciprofloxacin and levofloxacin These medicines generally need to be separated from antacids by an appropriate interval. ### Iron Supplements Antacids can reduce absorption of **oral iron**. ### Thyroid Medicines Antacids may interfere with the absorption of **levothyroxine**. ### Bisphosphonates Antacids can reduce absorption of medicines such as: * Alendronate * Risedronate ### Other Medicines Potential interactions can occur with other medicines whose absorption depends on stomach acidity or gastrointestinal conditions. As a general precaution, ask your pharmacist whether other oral medicines should be taken **at least 2–4 hours apart** from this antacid combination. The appropriate interval varies by medicine. Always inform your healthcare professional about all: * Prescription medicines * OTC medicines * Vitamins * Minerals * Herbal supplements --- ## STORAGE INFORMATION * Store according to the manufacturer's recommended conditions. * Keep in the original packaging. * Protect from excessive heat and direct sunlight. * Protect liquid formulations from inappropriate storage conditions. * If supplied as a suspension, keep the container tightly closed. * Shake liquid suspension well before each use. * Keep out of reach and sight of children. * Do not use after the expiry date. * Do not use the product if the packaging is damaged or tampered with. --- ## PRESCRIPTION STATUS **Prescription Status: Depends on Product and Local Regulations** Antacid combinations containing aluminium hydroxide and magnesium hydroxide may be available **over the counter** in some countries. However, formulations containing **oxethazaine** may have different dispensing requirements and may be prescription-only in some jurisdictions. Always follow local pharmacy and regulatory requirements. --- ## GENUINE MEDICINE ASSURANCE For safe and effective use, purchase this combination from a **licensed pharmacy or authorized medicine supplier**. Before purchasing or using the product, verify: * Product name * Active ingredients and strengths * Manufacturer * Batch/lot number * Manufacturing and expiry dates * Packaging and seal integrity * Regulatory information where applicable For liquid products, check that: * The seal is intact. * The suspension looks consistent with the manufacturer's description. * There are no unusual particles, discoloration, or changes in appearance. Do not use the product if it is: * Expired * Damaged * Tampered with * Missing batch/expiry information * Unusual in appearance If authenticity is uncertain, consult a licensed pharmacist or the relevant medicine regulatory authority. --- # FAQ – ALUMINIUM HYDROXIDE + MAGNESIUM HYDROXIDE + OXETHAZAINE + SIMETHICONE ### 1. What is Aluminium Hydroxide 300 mg + Magnesium Hydroxide 150 mg + Oxethazaine 10 mg + Simethicone 125 mg used for? It is used for symptomatic relief of **acidity, heartburn, acid indigestion, painful stomach irritation, gas, and bloating**. ### 2. Is this medicine an antacid? Yes. Aluminium hydroxide and magnesium hydroxide are **antacids** that neutralize excess stomach acid. ### 3. What is Oxethazaine used for? Oxethazaine is a **local anesthetic** that temporarily reduces pain and burning sensations in the gastrointestinal tract. ### 4. What is Simethicone used for? Simethicone helps reduce **gas, bloating, and abdominal discomfort** by helping gas bubbles combine and pass through the digestive tract more easily. ### 5. Can this medicine help with heartburn? Yes. The aluminium hydroxide and magnesium hydroxide components neutralize stomach acid and can provide temporary relief from heartburn. ### 6. Can this medicine help with gastritis? It may temporarily relieve acid-related burning and discomfort associated with gastritis, but it does not necessarily treat the underlying cause of gastritis. ### 7. Can this medicine help with gas and bloating? Yes. **Simethicone** is included specifically to help relieve gas-related bloating and discomfort. ### 8. Does this medicine cure acid reflux? No. It can provide temporary symptom relief but does not necessarily treat the underlying cause of **GERD or chronic acid reflux**. ### 9. Can this medicine be used every day? Regular prolonged use should be avoided unless recommended by a healthcare professional. Persistent acidity or abdominal pain requires evaluation of the underlying cause. ### 10. Can this medicine cause constipation? Yes. **Aluminium hydroxide can cause constipation** in some people. ### 11. Can this medicine cause diarrhea? Yes. **Magnesium hydroxide can cause loose stools or diarrhea**, particularly at higher doses. ### 12. Why are aluminium hydroxide and magnesium hydroxide combined? The two antacids have complementary effects. Aluminium hydroxide may cause constipation, while magnesium hydroxide may loosen stools, so combining them can provide effective acid neutralization with a more balanced effect on bowel movements. ### 13. Can I take this medicine with antibiotics? Some antibiotics interact with aluminium and magnesium because antacids can reduce their absorption. Ask your pharmacist about appropriate separation between the medicines. ### 14. Can I take this medicine with iron supplements? Antacids can reduce the absorption of oral iron. They should generally be taken at separate times according to professional advice. ### 15. Can I take this medicine with Levothyroxine? Aluminium- and magnesium-containing antacids can reduce levothyroxine absorption. They should be separated appropriately, commonly by several hours, according to your healthcare professional's instructions. ### 16. Can people with kidney disease take this medicine? People with significant kidney impairment should **consult a healthcare professional before use**, because aluminium and magnesium can accumulate when kidney function is reduced. ### 17. Can pregnant women take this medicine? Pregnant women should consult a healthcare professional before using this combination, especially for repeated or prolonged treatment. ### 18. Can this medicine be used while breastfeeding? Ask a healthcare professional before prolonged use while breastfeeding. ### 19. Can children take this medicine? Children should only use this combination when an appropriate dose has been recommended by a healthcare professional. ### 20. How quickly does this medicine work? The antacid components can begin neutralizing stomach acid relatively quickly, while simethicone acts locally on gas bubbles. The duration of relief varies between individuals. ### 21. Can this medicine be taken on an empty stomach? The appropriate timing depends on the specific formulation and indication. Follow the manufacturer's instructions or your healthcare professional's advice. ### 22. Should liquid antacid suspension be shaken before use? Yes. If the product is supplied as a suspension, **shake the bottle well before each dose** to ensure the ingredients are evenly distributed. ### 23. What happens if I take too much of this medicine? Excessive use can cause gastrointestinal symptoms and, particularly in people with kidney impairment, potentially serious **electrolyte disturbances or aluminium/magnesium accumulation**. Seek medical advice if a significant overdose occurs. ### 24. Is this medicine available without a prescription? Some antacid formulations are available OTC, but products containing **oxethazaine** may have different prescription requirements depending on the country. ### 25. When should I see a doctor instead of using an antacid? Seek medical evaluation for persistent or severe symptoms, difficulty swallowing, repeated vomiting, unexplained weight loss, vomiting blood, black stools, severe abdominal pain, or heartburn that occurs frequently. --- ## MEDICAL DISCLAIMER This information about **Aluminium Hydroxide 300 mg + Magnesium Hydroxide 150 mg + Oxethazaine 10 mg + Simethicone 125 mg** is provided for general educational and informational purposes only. It is **not a substitute for professional medical advice, diagnosis, or treatment**. This medicine is intended primarily for **symptomatic gastrointestinal relief**. Persistent heartburn, severe abdominal pain, recurrent vomiting, gastrointestinal bleeding, difficulty swallowing, or unexplained weight loss may indicate an underlying condition requiring medical evaluation. People with **kidney disease, significant electrolyte abnormalities, or other chronic medical conditions** should consult a healthcare professional before using this combination, particularly for prolonged periods. Antacids can interact with many oral medicines by changing their absorption. Maintain appropriate separation from interacting medicines as advised by your doctor or pharmacist. **Do not exceed the recommended dose or use this product continuously for prolonged periods without medical advice.** **Always read the product label/package insert and follow your doctor's or pharmacist's instructions.**